Trophoblast Differentiation: Progenitor Cells, Fusion and Migration – A Workshop Report

Challenge lies ahead in unravelling the role played by trophoblast and its repertoire of expressed genes in normal human placental development, growth and pathology. Specific technical advances will clearly be required for characterisation of function. In particular, improvements in our repertoire o...

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Bibliographic Details
Published in:Placenta (Eastbourne) 2006-04, Vol.27, p.141-143
Main Authors: Aplin, J.D., Straszewski-Chavez, S.L., Kalionis, B., Dunk, C., Morrish, D., Forbes, K., Baczyk, D., Rote, N., Malassine, A., Knöfler, M.
Format: Article
Language:English
Subjects:
Cell Communication
Cell Differentiation
Cell Fusion
Cell Lineage
Cell Movement
Differentiation
Gene Expression Regulation, Developmental
Humans
Migration
Stem Cells - physiology
Trophoblast
Trophoblasts - physiology
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Summary:Challenge lies ahead in unravelling the role played by trophoblast and its repertoire of expressed genes in normal human placental development, growth and pathology. Specific technical advances will clearly be required for characterisation of function. In particular, improvements in our repertoire of in vitro models are needed before many of the key questions can be answered. Recent advances in the study of human trophoblast differentiation are discussed.
ISSN:0143-4004
1532-3102
DOI:10.1016/j.placenta.2006.01.011