Aspects of computer-aided detection (CAD) and volumetry of pulmonary nodules using multislice CT

With the superb spatial resolution of modern multislice CT scanners and their ability to complete a thoracic scan within one breath-hold, software algorithms for computer-aided detection (CAD) of pulmonary nodules are now reaching high sensitivity levels at moderate false positive rates. A number of...

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Bibliographic Details
Published in:British journal of radiology 2005, Vol.78 (suppl_1), p.S46-S56
Main Authors: WIEMKER, R, ROGALLA, P, BLAFFERT, T, SIFRI, D, HAY, O, SHAH, E, TRUYEN, R, FLEITER, T
Format: Article
Language:English
Subjects:
Biological and medical sciences
Diagnosis, Differential
False Positive Reactions
Humans
Lung Diseases - diagnostic imaging
Lung Diseases - pathology
Lung Neoplasms - diagnostic imaging
Lung Neoplasms - pathology
Medical sciences
Pneumology
Radiographic Image Interpretation, Computer-Assisted - methods
Tomography, X-Ray Computed - methods
Tumors of the respiratory system and mediastinum
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Summary:With the superb spatial resolution of modern multislice CT scanners and their ability to complete a thoracic scan within one breath-hold, software algorithms for computer-aided detection (CAD) of pulmonary nodules are now reaching high sensitivity levels at moderate false positive rates. A number of pilot studies have shown that CAD modules can successfully find overlooked pulmonary nodules and serve as a powerful tool for diagnostic quality assurance. Equally important are tools for fast and accurate three-dimensional volume measurement of detected nodules. These allow monitoring of nodule growth between follow-up examinations for differential diagnosis and response to oncological therapy. Owing to decreasing partial volume effect, nodule volumetry is more accurate with high resolution CT data. Several studies have shown the feasibility and robustness of automated matching of corresponding nodule pairs between follow-up examinations. Fast and automated growth rate monitoring with only few reader interactions also adds to diagnostic quality assurance.
ISSN:0007-1285
1748-880X
DOI:10.1259/bjr/30281702