Primary pulmonary lymphoma disguised as asthma

Primary pulmonary lymphomas (PPL) only constitute 4% of extra-nodal, non-Hodgkin lymphomas (NHL), less than 1% of NHL in general, and between 0.5% and 1% of malignant pulmonary neoplasms. Fifty-eight to 87% of cases of this extremely uncommon disease are low-grade B-cell lymphomas and 11%-19% are hi...

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Bibliographic Details
Published in:Acta chirurgica belgica 2006, Vol.106 (1), p.127-129
Main Authors: SIRMAH, M, KALAC, N, AGACKIRAN, Y, KAYA, S
Format: Article
Language:English
Subjects:
Asthma - diagnosis
Asthma - etiology
Biological and medical sciences
Bronchoscopy
Diagnosis, Differential
Female
General aspects
Hematologic and hematopoietic diseases
Humans
Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis
Lung Neoplasms - complications
Lung Neoplasms - pathology
Lymphoma, B-Cell - complications
Lymphoma, B-Cell - pathology
Medical sciences
Middle Aged
Tomography, X-Ray Computed
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Summary:Primary pulmonary lymphomas (PPL) only constitute 4% of extra-nodal, non-Hodgkin lymphomas (NHL), less than 1% of NHL in general, and between 0.5% and 1% of malignant pulmonary neoplasms. Fifty-eight to 87% of cases of this extremely uncommon disease are low-grade B-cell lymphomas and 11%-19% are high-grade or large B-cell lymphomas. The prognosis for.high-grade or large B-cell lymphomas is worse than for low-grade lymphomas; respiratory and general symptoms are usually present. However asthmatic symptoms are not often found in their clinic. We report the case of a 49-year old woman with resistant asthma clinic in the form of wheezing, dyspnea and non-productive painless cough; associated with an irregular lobulated mass with air bronchograms in the lower lobe of the right lung. Histological diagnosis showed a pattern of high-grade B-cell lymphoma and all asthmatic symptoms disappeared following gross total resection of this lesion.
ISSN:0001-5458
DOI:10.1080/00015458.2006.11679855