Role of Dietary Salt Intake in Posttransplant Hypertension With Tacrolimus-Based Immunosuppression

Dietary salt is an important contributor to hypertension in the general population. While its role in cyclosporine-induced hypertension is minimal, its role in tacrolimus-based immunosuppression has not been defined. We measured the 24-hour urine sodium excretion as an estimate of intake in a group...

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Bibliographic Details
Published in:Transplantation proceedings 2005-05, Vol.37 (4), p.1896-1897
Main Authors: Prasad, G.V.R., Huang, M., Nash, M.M., Zaltzman, J.S.
Format: Article
Language:English
Subjects:
Analysis of Variance
Biological and medical sciences
Blood Pressure - drug effects
Diseases of the digestive system
Fundamental and applied biological sciences. Psychology
Fundamental immunology
Humans
Hypertension - physiopathology
Immunosuppressive Agents - therapeutic use
Kidney Transplantation - physiology
Medical sciences
Postoperative Complications - physiopathology
Proteinuria
Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)
Sodium - urine
Sodium Chloride, Dietary - pharmacology
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Tacrolimus - therapeutic use
Tissue, organ and graft immunology
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Summary:Dietary salt is an important contributor to hypertension in the general population. While its role in cyclosporine-induced hypertension is minimal, its role in tacrolimus-based immunosuppression has not been defined. We measured the 24-hour urine sodium excretion as an estimate of intake in a group of stable renal transplant recipients on tacrolimus ( N = 143) who had serum creatinine fluctuations
ISSN:0041-1345
1873-2623
DOI:10.1016/j.transproceed.2005.04.002