Motor cortex excitability after thalamic infarction

Transcranial magnetic stimulation was used to map hand muscle representations in the motor cortex of a patient in whom infarction of the sensory thalamus deprived the sensorimotor cortex of sensory input. The threshold for activation of the motor cortex on the affected side was higher and the cortic...

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Bibliographic Details
Published in:Journal of clinical neuroscience 2005-05, Vol.12 (4), p.469-472
Main Authors: Miles, T.S., Ridding, M.C., McKay, D., Thompson, P.D.
Format: Article
Language:English
Subjects:
Adult
Brain Infarction - pathology
Brain Infarction - physiopathology
Electromyography - methods
Evoked Potentials, Motor - physiology
Evoked Potentials, Motor - radiation effects
Female
Functional Laterality
Humans
Magnetic Resonance Imaging - methods
Motor Cortex - physiopathology
Muscle, Skeletal - physiopathology
plasticity
sensorimotor cortex
thalamic stroke
Thalamus - pathology
Transcranial Magnetic Stimulation - methods
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Description
Summary:Transcranial magnetic stimulation was used to map hand muscle representations in the motor cortex of a patient in whom infarction of the sensory thalamus deprived the sensorimotor cortex of sensory input. The threshold for activation of the motor cortex on the affected side was higher and the cortical representational maps of individual muscles were less well defined than those on the normal side. It is concluded that electrophysiological changes in cortical organisation can be demonstrated following withdrawal of, or imbalance in sensory afferent activity to the cerebral cortex in humans.
ISSN:0967-5868
1532-2653
DOI:10.1016/j.jocn.2005.01.002