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occurrence of congenital heart defects in an inbred herd of pigs in Australia

Objective To report on the first case of congenital heart defects in pigs in Australia. Design Retrospective analysis of case records from an inbred herd of “Westran’ pigs at the University of Sydney, between January 2001 and December 2004. Detailed gross and histological examination of 15 hearts fr...

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Bibliographic Details
Published in:Australian veterinary journal 2006-04, Vol.84 (4), p.129-133
Main Authors: Holyoake, P.K, Stevenson, J, Moran, C, Stokes, R, Kirk, E.P, Sugo, E, Hawthorne, W.J
Format: Article
Language:English
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Summary:Objective To report on the first case of congenital heart defects in pigs in Australia. Design Retrospective analysis of case records from an inbred herd of “Westran’ pigs at the University of Sydney, between January 2001 and December 2004. Detailed gross and histological examination of 15 hearts from pigs that had died or were euthanased in 2004. Case Details The necropsy records from a population of 471 pigs that had died (106 pigs) or were euthanased for research purposes (365 pigs) were analysed and the incidence of heart defects recorded, together with basic demographic data. No attempts were made to diagnose the condition in live pigs. Results Congenital heart defects were diagnosed in 6.4% of pigs but this is likely to be an underestimate of the incidence of the deformity. Eighteen pigs died on the farm as a result of the defect, and 12 pigs were diagnosed with the defect as an incidental finding. The most common abnormality seen at necropsy was a sac‐like dilatation on the right lateral surface of the right atrium. This was associated with secondary deformity and hypoplasia of the adjacent left ventricle, interventricular region and part of the right ventricle. All hearts showed atrial septal defects of varying size. Conclusion This is the first reported case of congenital heart defects in pigs in Australia, and one of less than five reported cases of atrial septal defects in pigs in the world. The authors conclude that there may be an element of genetic predisposition to the malformation, since it has only been reported in this inbred line of pigs.
ISSN:0005-0423
1751-0813
DOI:10.1111/j.1751-0813.2006.tb13395.x