Autosomal recessive plasma cell panniculitis with morphea-like clinical manifestation

Two siblings had hyperpigmented indurations over the inner aspects of both thighs extending to the lower abdomen. Skin biopsy showed plasma cell panniculitis favoring a diagnosis of morphea profundus. Family history of consanguinity was present, but both parents were unaffected. To our knowledge thi...

Full description

Saved in:
Bibliographic Details
Published in:Journal of the American Academy of Dermatology 2006-05, Vol.54 (5), p.S189-S191
Main Authors: Hamadah, Issam R., Banka, Nusrat
Format: Article
Language:English
Subjects:
Abdomen
Adolescent
Biological and medical sciences
Child
Consanguinity
Dermatology
Female
Genes, Dominant
Humans
Male
Medical sciences
Panniculitis - genetics
Panniculitis - pathology
Plasma Cells - pathology
Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis
Scleroderma, Localized - pathology
Skin involvement in other diseases. Miscellaneous. General aspects
Thigh
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Two siblings had hyperpigmented indurations over the inner aspects of both thighs extending to the lower abdomen. Skin biopsy showed plasma cell panniculitis favoring a diagnosis of morphea profundus. Family history of consanguinity was present, but both parents were unaffected. To our knowledge this is the first report of autosomal recessive plasma cell panniculitis with the clinical manifestations of morphea.
ISSN:0190-9622
1097-6787
DOI:10.1016/j.jaad.2005.06.032