The Association Between Obesity and the Frailty Syndrome in Older Women: The Women's Health and Aging Studies

Objectives: To determine whether obesity is associated with the frailty phenotype and, if so, whether comorbid conditions or inflammatory markers explain this association. Design: Cross‐sectional analysis of baseline data from the Women's Health and Aging Studies I (1992) and II (1994), complem...

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Bibliographic Details
Published in:Journal of the American Geriatrics Society (JAGS) 2005-06, Vol.53 (6), p.927-934
Main Authors: Blaum, Caroline S., Xue, Qian Li, Michelon, Elisabete, Semba, Richard D., Fried, Linda P.
Format: Article
Language:English
Subjects:
Activities of Daily Living
Age Distribution
Aged
Aging
Arthritis - epidemiology
Baltimore
Biological and medical sciences
Body Mass Index
Cardiovascular Diseases - epidemiology
Comorbidity
Cross-Sectional Studies
Diabetes Mellitus - epidemiology
Elderly women
Female
Frail
Frail Elderly - statistics & numerical data
frailty
General aspects
Genotype & phenotype
Geriatrics
Humans
Logistic Models
Maryland - epidemiology
Medical sciences
Metabolic diseases
Obesity
Obesity - epidemiology
Older people
older women
overweight and obese
Prevalence
Pulmonary Disease, Chronic Obstructive - epidemiology
Risk factors
Socioeconomic Factors
Syndrome
USA
Women
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Summary:Objectives: To determine whether obesity is associated with the frailty phenotype and, if so, whether comorbid conditions or inflammatory markers explain this association. Design: Cross‐sectional analysis of baseline data from the Women's Health and Aging Studies I (1992) and II (1994), complementary population‐based studies. Setting: Twelve contiguous ZIP code areas in Baltimore, Maryland. Participants: Five hundred ninety‐nine community‐dwelling women aged 70 to 79 with a body mass index (BMI) greater than 18.5 kg/m2. Measurements: The dependent variables were the frailty syndrome, including prefrailty, defined as presence of one or two of five frailty indicators (weakness, slowness, weight loss, low physical activity, exhaustion), and frailty, defined as three or more indicators. Independent variables included BMI, categorized using World Health Organization criteria as normal (18.5 to
ISSN:0002-8614
1532-5415
DOI:10.1111/j.1532-5415.2005.53300.x