Atypical manifestations of multiple myeloma: Radiological appearance

Diagnostic procedures performed on patients with multiple myeloma typically reveal lytic bone lesions, osteopenia or osteoporosis, bone marrow infiltration by plasma cells as well as overproduction of immunoglobulin or light chains in the serum or urine. Skeletal manifestations are extremely variabl...

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Bibliographic Details
Published in:European journal of radiology 2006-05, Vol.58 (2), p.280-285
Main Authors: Heß, Thomas, Egerer, Gerlinde, Kasper, Bernd, Rasul, Kakil Ibrahim, Goldschmidt, Hartmut, Kauffmann, G.W.
Format: Article
Language:English
Subjects:
Abdominal Neoplasms - diagnosis
Abdominal Neoplasms - drug therapy
Abdominal Neoplasms - radiotherapy
Aged
Amyloidosis - complications
Amyloidosis - diagnosis
Amyloidosis - drug therapy
Atypical manifestations
Biological and medical sciences
Diagnosis, Differential
Fatal Outcome
Female
Hematologic and hematopoietic diseases
Humans
Immunodeficiencies. Immunoglobulinopathies
Immunoglobulinopathies
Immunopathology
Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis
Liver - pathology
Liver Neoplasms - diagnosis
Liver Neoplasms - secondary
Lung - diagnostic imaging
Lung Neoplasms - diagnosis
Lung Neoplasms - radiotherapy
Magnetic Resonance Imaging - methods
Male
Medical sciences
Middle Aged
Multiple myeloma
Multiple Myeloma - diagnosis
Multiple Myeloma - drug therapy
Multiple Myeloma - radiotherapy
Nasopharyngeal Neoplasms - diagnosis
Nasopharyngeal Neoplasms - drug therapy
Peritoneal Cavity - diagnostic imaging
Peritoneal Neoplasms - diagnosis
Peritoneal Neoplasms - drug therapy
Radiography, Abdominal - methods
Skeletal radiology
Sphenoid Sinus - pathology
Spinal Neoplasms - diagnosis
Spinal Neoplasms - pathology
Spinal Neoplasms - radiotherapy
Tomography, X-Ray Computed - methods
Treatment Outcome
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Description
Summary:Diagnostic procedures performed on patients with multiple myeloma typically reveal lytic bone lesions, osteopenia or osteoporosis, bone marrow infiltration by plasma cells as well as overproduction of immunoglobulin or light chains in the serum or urine. Skeletal manifestations are extremely variable and the unusual forms have been described extensively. Extramedullary plasma-cell tumours (plasmocytoma) are found in about 5% of newly diagnosed patients with multiple myelomas. In this paper we present eight patients with atypical forms of multiple myeloma.
ISSN:0720-048X
1872-7727
DOI:10.1016/j.ejrad.2005.11.015