Systemic vasculitis associated with Fasciola hepatica infection

We report the case of a 50-year-old man who presented with systemic vasculitis associated with Fasciola hepatica infection. The patient presented with severe skin, kidney, spleen, ophthalmic, and neurological compromise. An immunological examination for primary vasculitis was negative and other infe...

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Bibliographic Details
Published in:Scandinavian journal of rheumatology 2006-04, Vol.35 (2), p.143-146
Main Authors: Llanos, C., Soto, L., Sabugo, F., Gallegos, I., Valenzuela, O., Verdaguer, J., Cuchacovich, M.
Format: Article
Language:English
Subjects:
Animals
Anthelmintics - therapeutic use
Antibodies, Helminth - analysis
Benzimidazoles - therapeutic use
Biological and medical sciences
Diagnosis, Differential
Enzyme-Linked Immunosorbent Assay
Fasciola hepatica
Fasciola hepatica - immunology
Fasciola hepatica - isolation & purification
Fascioliasis - complications
Fascioliasis - drug therapy
Fascioliasis - parasitology
Follow-Up Studies
Humans
Male
Medical sciences
Middle Aged
Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis
Vasculitis - diagnosis
Vasculitis - drug therapy
Vasculitis - etiology
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Summary:We report the case of a 50-year-old man who presented with systemic vasculitis associated with Fasciola hepatica infection. The patient presented with severe skin, kidney, spleen, ophthalmic, and neurological compromise. An immunological examination for primary vasculitis was negative and other infections were discounted by microbiological and serological analyses. The patient was treated with steroids without clinical response. The Fasciola hepatica infection was confirmed by the presence of specific immunoglobulin G (IgG) serum antibodies detected by a quantitative enzyme-linked immunosorbent assay (ELISA) with an optical density (OD) of 0.483 OD units (normal value
ISSN:0300-9742
1502-7732
DOI:10.1080/03009740500303231