MSight: An image analysis software for liquid chromatography-mass spectrometry

Images obtained from high‐throughput mass spectrometry (MS) contain information that remains hidden when looking at a single spectrum at a time. Image processing of liquid chromatography‐MS datasets can be extremely useful for quality control, experimental monitoring and knowledge extraction. The im...

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Bibliographic Details
Published in:Proteomics (Weinheim) 2005-06, Vol.5 (9), p.2381-2384
Main Authors: Palagi, Patricia M., Walther, Daniel, Quadroni, Manfredo, Catherinet, Sébastien, Burgess, Jennifer, Zimmermann-Ivol, Catherine G., Sanchez, Jean-Charles, Binz, Pierre-Alain, Hochstrasser, Denis F., Appel, Ron D.
Format: Article
Language:English
Subjects:
Analysis
Analytical, structural and metabolic biochemistry
Biological and medical sciences
Chromatography, Liquid
Electrophoresis, Gel, Two-Dimensional
Fundamental and applied biological sciences. Psychology
Image Processing, Computer-Assisted
Liquid chromatography
Mass spectrometry
Miscellaneous
Peptides - analysis
Proteins
Proteome - analysis
Proteome imaging
Software
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
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Summary:Images obtained from high‐throughput mass spectrometry (MS) contain information that remains hidden when looking at a single spectrum at a time. Image processing of liquid chromatography‐MS datasets can be extremely useful for quality control, experimental monitoring and knowledge extraction. The importance of imaging in differential analysis of proteomic experiments has already been established through two‐dimensional gels and can now be foreseen with MS images. We present MSight, a new software designed to construct and manipulate MS images, as well as to facilitate their analysis and comparison.
ISSN:1615-9853
1615-9861
DOI:10.1002/pmic.200401244