Mycoplasma genitalium is associated with symptomatic urethritis

In order to further investigate the epidemiology of Mycoplasma genitalium, 680 men attending departments of genitourinary medicine in Bristol, Bath and Truro were studied. M. genitalium was detected in 36 men (5.3%) and was present at all three clinics. Clinically, both urethritis and the presence o...

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Bibliographic Details
Published in:International journal of STD & AIDS 2006-05, Vol.17 (5), p.285-288
Main Authors: LEUNG, A, EASTICK, K, HADDON, L. E, HORN, C. K, AHUJA, D, HORNER, P. J
Format: Article
Language:English
Subjects:
Adult
AIDS/HIV
Bacterial diseases
Bacterial diseases of the genital system
Biological and medical sciences
Chlamydia trachomatis - isolation & purification
Epidemiology. Vaccinations
General aspects
Human bacterial diseases
Humans
Infectious diseases
Life Style
Male
Medical sciences
Multivariate Analysis
Mycoplasma genitalium
Mycoplasma genitalium - isolation & purification
Mycoplasma Infections - epidemiology
Mycoplasma Infections - pathology
Neisseria gonorrhoeae - isolation & purification
Prevalence
Risk Factors
Sexual Behavior
Sexually Transmitted Diseases, Bacterial - epidemiology
Sexually Transmitted Diseases, Bacterial - pathology
United Kingdom - epidemiology
Urethritis - epidemiology
Urethritis - microbiology
Urethritis - pathology
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Summary:In order to further investigate the epidemiology of Mycoplasma genitalium, 680 men attending departments of genitourinary medicine in Bristol, Bath and Truro were studied. M. genitalium was detected in 36 men (5.3%) and was present at all three clinics. Clinically, both urethritis and the presence of a urethral discharge and/or dysuria, but not penile irritation were independently associated with the detection of M. genitalium, the former being with the strongest association (odds ratio [OR] 10.76, 95% confidence interval [CI] [3.10–37.29], P < 0.0001; OR 3.01, 95% CI [1.28–7.05], P = 0.011 and OR 1.28, 95% CI [0.61–2.69], P = 0.51, respectively). In men with urethritis, those with a discharge and/or dysuria were more likely to have M. genitalium detected (OR 2.61, 95% CI [1.09–6.25], P = 0.032). We found no association with younger age or a recent change of sexual partner. In conclusion, M. genitalium is associated with symptomatic urethritis.
ISSN:0956-4624
1758-1052
DOI:10.1258/095646206776790231