Validation of Predictors of Intraprocedural Stent Thrombosis in the Drug-Eluting Stent Era

Although predictors of acute intraprocedural stent thrombosis (IPST) in the drug-eluting stent era have been proposed, external validation is lacking. We thus analyzed the occurrence of IPST in the RECIPE study and found that, among 1,320 patients who underwent drug-eluting stent implantation, IPST...

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Bibliographic Details
Published in:The American journal of cardiology 2005-06, Vol.95 (12), p.1466-1468
Main Authors: Biondi-Zoccai, Giuseppe G.L., Sangiorgi, Giuseppe M., Chieffo, Alaide, Vittori, Guido, Falchetti, Elena, Margheri, Massimo, Barbagallo, Rossella, Tamburino, Corrado, Remigi, Enrico, Briguori, Carlo, Iakovou, Ioannis, Agostoni, Pierfrancesco, Tsagalou, Elephteria, Melzi, Gloria, Michev, Iassen, Airoldi, Flavio, Montorfano, Matteo, Carlino, Mauro, Colombo, Antonio
Format: Article
Language:English
Subjects:
Acute Disease
Anticoagulants - therapeutic use
Antineoplastic Agents, Phytogenic - therapeutic use
Biological and medical sciences
Blood Vessel Prosthesis Implantation - instrumentation
Cardiology
Cardiology. Vascular system
Coated Materials, Biocompatible
Coronary Angiography
Coronary Stenosis - surgery
Coronary Thrombosis - diagnosis
Coronary Thrombosis - prevention & control
Drug Therapy, Combination
Electrocardiography
Female
Heparin - therapeutic use
Humans
Inhibitor drugs
Intraoperative Complications
Male
Medical procedures
Medical sciences
Middle Aged
Paclitaxel - therapeutic use
Platelet Aggregation Inhibitors - therapeutic use
Predictive Value of Tests
Pyridines - therapeutic use
Retrospective Studies
Stents
Thrombolytic Therapy
Ticlopidine - analogs & derivatives
Ticlopidine - therapeutic use
Treatment Outcome
Validation studies
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Description
Summary:Although predictors of acute intraprocedural stent thrombosis (IPST) in the drug-eluting stent era have been proposed, external validation is lacking. We thus analyzed the occurrence of IPST in the RECIPE study and found that, among 1,320 patients who underwent drug-eluting stent implantation, IPST occurred in 6 (0.5%), with in-hospital major adverse events in 4 (67%). IPST was predicted by number and total length of implanted stents, baseline minimal lumen diameter, and, in a pooled analysis that incorporated values from the present study and a previous study, use of elective glycoprotein IIb/IIIa inhibitors. Such results may provide useful information to guide prevention of this complication.
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2005.01.099