Invited Review: Bovine Milk Fat Globule Membrane as a Potential Nutraceutical

For the last 15 yr, a great deal of knowledge has been accumulated on health beneficial factors, protein and nonprotein, of bovine milk fat globule membrane (MFGM). Among the health-beneficial components of the MFGM are cholesterolemia-lowering factor, inhibitors of cancer cell growth, vitamin binde...

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Bibliographic Details
Published in:Journal of dairy science 2005-07, Vol.88 (7), p.2289-2294
Main Author: Spitsberg, V. L
Format: Article
Language:English
Subjects:
Animal productions
Animals
Anti-Infective Agents
Anticholesteremic Agents
antineoplastic agents
Biological and medical sciences
bovine milk fat globule membrane
Breast Neoplasms - prevention & control
Butyrophilins
Cattle
cholesterolemia
Coronary Disease - prevention & control
Encephalomyelitis, Autoimmune, Experimental - prevention & control
Escherichia coli
fatty acid-binding proteins
Food industries
functional foods
Fundamental and applied biological sciences. Psychology
Glycolipids - administration & dosage
Glycolipids - chemistry
Glycolipids - therapeutic use
Glycoproteins - administration & dosage
Glycoproteins - chemistry
Glycoproteins - therapeutic use
Health Promotion
Helicobacter Infections - prevention & control
Helicobacter pylori
Humans
literature reviews
Membrane Glycoproteins - administration & dosage
Milk and cheese industries. Ice creams
milk anticancer protein
Neoplasms - prevention & control
Nutritional Physiological Phenomena
phospholipid
Phospholipids - administration & dosage
Terrestrial animal productions
Vertebrates
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Summary:For the last 15 yr, a great deal of knowledge has been accumulated on health beneficial factors, protein and nonprotein, of bovine milk fat globule membrane (MFGM). Among the health-beneficial components of the MFGM are cholesterolemia-lowering factor, inhibitors of cancer cell growth, vitamin binders, inhibitor of Helicobacter pylori, inhibitor of beta-glucuronidase of the intestinal Escherichia coli, xanthine oxidase as a bactericidal agent, butyrophilin as a possible suppressor of multiple sclerosis, and phospholipids as agents against colon cancer, gastrointestinal pathogens, Alzheimer's disease, depression, and stress. All of the above compel us to consider bovine MFGM as a potential nutraceutical.
ISSN:0022-0302
1525-3198
DOI:10.3168/jds.S0022-0302(05)72906-4