A Close-up of the ESCRTs

The ESCRT protein complexes assemble on the endosome into a protein network that sorts ubiquitinated transmembrane proteins into lumenal vesicles of the compartment. New structural information highlights the complexity of the ESCRT network.

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Bibliographic Details
Published in:Developmental cell 2006-05, Vol.10 (5), p.547-548
Main Author: Babst, Markus
Format: Article
Language:English
Subjects:
Biological and medical sciences
Cell differentiation, maturation, development, hematopoiesis
Cell physiology
Endosomes - chemistry
Endosomes - metabolism
Fundamental and applied biological sciences. Psychology
Humans
Molecular and cellular biology
Multiprotein Complexes - chemistry
Multiprotein Complexes - metabolism
Protein Transport
Vesicular Transport Proteins - chemistry
Vesicular Transport Proteins - metabolism
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Description
Summary:The ESCRT protein complexes assemble on the endosome into a protein network that sorts ubiquitinated transmembrane proteins into lumenal vesicles of the compartment. New structural information highlights the complexity of the ESCRT network.
ISSN:1534-5807
1878-1551
DOI:10.1016/j.devcel.2006.04.013