Myocardial enhancement pattern in patients with acute myocardial infarction on two-phase contrast-enhanced ECG-gated multidetector-row computed tomography

To evaluate the myocardial enhancement pattern of the left ventricle on two-phase contrast-enhanced electrocardiogram (ECG)-gated multidetector computed tomography (MDCT) images in patients with acute myocardial infarction (AMI). Two-phase contrast-enhanced ECG-gated MDCT examinations were performed...

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Bibliographic Details
Published in:Clinical radiology 2006-05, Vol.61 (5), p.417-422
Main Authors: Ko, S.M., Seo, J.B., Hong, M.K., Do, K.H., Lee, S.H., Lee, J.S., Song, J.W., Park, S.J., Park, S.W., Lim, T.H.
Format: Article
Language:English
Subjects:
Adult
Aged
Biological and medical sciences
Cardiology. Vascular system
Contrast Media
Coronary Angiography - methods
Coronary Circulation - physiology
Coronary heart disease
Electrocardiography - methods
Female
Heart
Heart - diagnostic imaging
Heart - physiopathology
Humans
Male
Medical sciences
Middle Aged
Myocardial Infarction - diagnostic imaging
Myocardial Infarction - physiopathology
Prospective Studies
Radiographic Image Enhancement - methods
Tomography, X-Ray Computed - methods
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Summary:To evaluate the myocardial enhancement pattern of the left ventricle on two-phase contrast-enhanced electrocardiogram (ECG)-gated multidetector computed tomography (MDCT) images in patients with acute myocardial infarction (AMI). Two-phase contrast-enhanced ECG-gated MDCT examinations were performed in 16 patients with AMI. The presence, location and pattern of myocardial enhancement were evaluated. MDCT findings were compared with the catheter angiographic results. Subendocardial ( n=9) or transmural ( n=6) area of early perfusion defects of the myocardium was detected in 15 of 16 patients (94%) on early-phase CT images. Variable delayed myocardial enhancement patterns on late-phase CT images were observed in 12 patients (75%): (1) subendocardial residual perfusion defect and subepicardial late enhancement ( n=6); (2) transmural late enhancement ( n=1); (3) isolated subendocardial late enhancement ( n=1); and (4) isolated subendocardial residual perfusion defect ( n=2). On catheter angiography, 14 of 15 corresponding coronary arteries showed significant stenosis. Variable abnormal myocardial enhancement pattern was seen on two-phase, contrast-enhanced ECG-gated MDCT in patients with AMI. Assessment of myocardial attenuation on CT angiography gives additional information of the location and extent of infarction.
ISSN:0009-9260
1365-229X
DOI:10.1016/j.crad.2005.11.011