Helicobacter pylori as cause of gastrointestinal disease in children with hemato-oncologic diseases

After documentation of a case of life threatening Helicobacter pylori (H. pylori) gastric ulcer in an adolescent girl on treatment for acute lymphoblastic leukaemia, we started to systematically look for gastro‐intestinal symptoms due to H. pylori infection in our cancer patients at G. Gaslini Child...

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Bibliographic Details
Published in:Pediatric Blood & Cancer 2006-07, Vol.47 (1), p.89-91
Main Authors: Castagnola, Elio, Calvillo, Michaela, Gigliotti, Anna Rita, Fioredda, Francesca, Hanau, Guia, Caviglia, Ilaria, Lanino, Edoardo, Dufour, Carlo
Format: Article
Language:English
Subjects:
Abdominal Pain - complications
Abdominal Pain - microbiology
Adolescent
Adult
Biological and medical sciences
BMT
Child
Child, Preschool
Female
Gastrointestinal Diseases - complications
Gastrointestinal Diseases - microbiology
General aspects
Helicobacter Infections - complications
Helicobacter pylori
Hematologic Diseases - complications
hematology/oncology
Hematopoietic Stem Cell Transplantation - adverse effects
Humans
Immunocompromised Host
infections in immunocompromised hosts
Male
Medical sciences
Neoplasms - complications
support care
Tumors
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Summary:After documentation of a case of life threatening Helicobacter pylori (H. pylori) gastric ulcer in an adolescent girl on treatment for acute lymphoblastic leukaemia, we started to systematically look for gastro‐intestinal symptoms due to H. pylori infection in our cancer patients at G. Gaslini Children's Hospital. During a period of 46 months, we observed 13 further cases of severe dyspepsia syndrome or gastro intestinal bleeding associated with presence of H. pylori faecal antigen. All patients recovered with appropriate therapy. H. pylori may represent a cause of severe gastrointestinal complications in children with cancer or following bone marrow transplant. © 2005 Wiley‐Liss, Inc.
ISSN:1545-5009
1545-5017
1096-911X
DOI:10.1002/pbc.20459