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Bilateral inguinal hernia with dislocation of great saphenous vein as complication of long‐standing granulomatous slack skin: a case report
Granulomatous slack skin (GSS) represents a rare variant of mycosis fungoides, histologically characterized by a variably deep T helper lymphocytes infiltrate with alteration of the dermal elastic tissue and consequent elastolysis, elastophagocytosis and numerous giant cells. Clinically, a developme...
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Published in: | Journal of the European Academy of Dermatology and Venereology 2006-05, Vol.20 (5), p.595-598 |
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creator | Benedetti, M Niebel, T Tinozzi, FP Vassallo, C Brazzelli, V Paulli, M Borroni, RG Borroni, G |
description | Granulomatous slack skin (GSS) represents a rare variant of mycosis fungoides, histologically characterized by a variably deep T helper lymphocytes infiltrate with alteration of the dermal elastic tissue and consequent elastolysis, elastophagocytosis and numerous giant cells. Clinically, a development of unelastic, slack skin, especially on flexural areas, is observed. Hereby, we describe a man with a 12‐year history of GSS. In 2002, for practical (limitation of movement, deambulation) and cosmetic reasons, he underwent the surgical excision of loose and sagging skinfold over inguinal area, and, afterwards, of the opposite affected inguinal skin. The surgical treatment of bilateral inguinal hernia with reposition of inguinal dislocated vasculature is also reported. In both cases the excised material confirmed the former diagnosis of GSS and revealed a very deep, muscular infiltrate of neoplastic lymphocytes. One year later, a new excision of GSS on the axillae was made. Now, after 2 years, deambulation keeps improving, although an initial relapse of the inguinal slack skin has been observed. |
doi_str_mv | 10.1111/j.1468-3083.2006.01575.x |
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Clinically, a development of unelastic, slack skin, especially on flexural areas, is observed. Hereby, we describe a man with a 12‐year history of GSS. In 2002, for practical (limitation of movement, deambulation) and cosmetic reasons, he underwent the surgical excision of loose and sagging skinfold over inguinal area, and, afterwards, of the opposite affected inguinal skin. The surgical treatment of bilateral inguinal hernia with reposition of inguinal dislocated vasculature is also reported. In both cases the excised material confirmed the former diagnosis of GSS and revealed a very deep, muscular infiltrate of neoplastic lymphocytes. One year later, a new excision of GSS on the axillae was made. Now, after 2 years, deambulation keeps improving, although an initial relapse of the inguinal slack skin has been observed.</description><identifier>ISSN: 0926-9959</identifier><identifier>EISSN: 1468-3083</identifier><identifier>DOI: 10.1111/j.1468-3083.2006.01575.x</identifier><identifier>PMID: 16684291</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Publishing Ltd</publisher><subject>Dermatologic Surgical Procedures ; elastolysis ; Granuloma - complications ; Granuloma - pathology ; Granuloma - surgery ; hernia ; Hernia, Inguinal - etiology ; Hernia, Inguinal - pathology ; Hernia, Inguinal - surgery ; Humans ; interferon alpha2a ; life style ; Male ; Middle Aged ; mycosis fungoides ; Mycosis Fungoides - complications ; Mycosis Fungoides - pathology ; Mycosis Fungoides - surgery ; Recurrence ; Saphenous Vein - pathology ; Skin - pathology ; Skin Neoplasms - complications ; Skin Neoplasms - pathology ; Skin Neoplasms - surgery ; slack skin</subject><ispartof>Journal of the European Academy of Dermatology and Venereology, 2006-05, Vol.20 (5), p.595-598</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3985-807a82d340d94620ab33c61892a673aead1de445d8241f055b168ae40495c3e3</citedby><cites>FETCH-LOGICAL-c3985-807a82d340d94620ab33c61892a673aead1de445d8241f055b168ae40495c3e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16684291$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Benedetti, M</creatorcontrib><creatorcontrib>Niebel, T</creatorcontrib><creatorcontrib>Tinozzi, FP</creatorcontrib><creatorcontrib>Vassallo, C</creatorcontrib><creatorcontrib>Brazzelli, V</creatorcontrib><creatorcontrib>Paulli, M</creatorcontrib><creatorcontrib>Borroni, RG</creatorcontrib><creatorcontrib>Borroni, G</creatorcontrib><title>Bilateral inguinal hernia with dislocation of great saphenous vein as complication of long‐standing granulomatous slack skin: a case report</title><title>Journal of the European Academy of Dermatology and Venereology</title><addtitle>J Eur Acad Dermatol Venereol</addtitle><description>Granulomatous slack skin (GSS) represents a rare variant of mycosis fungoides, histologically characterized by a variably deep T helper lymphocytes infiltrate with alteration of the dermal elastic tissue and consequent elastolysis, elastophagocytosis and numerous giant cells. Clinically, a development of unelastic, slack skin, especially on flexural areas, is observed. Hereby, we describe a man with a 12‐year history of GSS. In 2002, for practical (limitation of movement, deambulation) and cosmetic reasons, he underwent the surgical excision of loose and sagging skinfold over inguinal area, and, afterwards, of the opposite affected inguinal skin. The surgical treatment of bilateral inguinal hernia with reposition of inguinal dislocated vasculature is also reported. In both cases the excised material confirmed the former diagnosis of GSS and revealed a very deep, muscular infiltrate of neoplastic lymphocytes. One year later, a new excision of GSS on the axillae was made. Now, after 2 years, deambulation keeps improving, although an initial relapse of the inguinal slack skin has been observed.</description><subject>Dermatologic Surgical Procedures</subject><subject>elastolysis</subject><subject>Granuloma - complications</subject><subject>Granuloma - pathology</subject><subject>Granuloma - surgery</subject><subject>hernia</subject><subject>Hernia, Inguinal - etiology</subject><subject>Hernia, Inguinal - pathology</subject><subject>Hernia, Inguinal - surgery</subject><subject>Humans</subject><subject>interferon alpha2a</subject><subject>life style</subject><subject>Male</subject><subject>Middle Aged</subject><subject>mycosis fungoides</subject><subject>Mycosis Fungoides - complications</subject><subject>Mycosis Fungoides - pathology</subject><subject>Mycosis Fungoides - surgery</subject><subject>Recurrence</subject><subject>Saphenous Vein - pathology</subject><subject>Skin - pathology</subject><subject>Skin Neoplasms - complications</subject><subject>Skin Neoplasms - pathology</subject><subject>Skin Neoplasms - surgery</subject><subject>slack skin</subject><issn>0926-9959</issn><issn>1468-3083</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><recordid>eNqNkctu1DAUhi0EokPhFZBX7BLs-BIbiQUUykWV2FRsrTOOZ8ZTxw52QtsdL1CJZ-RJSJgRXYI3PpK__z-WPoQwJTWdz8t9TblUFSOK1Q0hsiZUtKK-eYBWfx8eohXRjay0FvoEPSllTwihVKjH6IRKqXij6QrdvfUBRpchYB-3k4_zsHM5esDXftzhzpeQLIw-RZw2eJsdjLjAsHMxTQV_dz5iKNimfgj-ngspbn_9-FlGiN3cO-cgTiH1MC6pEsBe4XLl4ysM2EJxOLsh5fEperSBUNyz432KLs_fX559rC6-fPh09uaiskwrUSnSgmo6xkmnuWwIrBmzkirdgGwZOOho5zgXnWo43RAh1lQqcJxwLSxz7BS9ONQOOX2bXBlN74t1IUB08_-MbLVgmpF_glS3bcvaZgbVAbQ5lZLdxgzZ95BvDSVmUWb2ZjFjFjNmUWb-KDM3c_T5cce07l13Hzw6moHXB-DaB3f738Xm87uvy8R-A-f8qDM</recordid><startdate>200605</startdate><enddate>200605</enddate><creator>Benedetti, M</creator><creator>Niebel, T</creator><creator>Tinozzi, FP</creator><creator>Vassallo, C</creator><creator>Brazzelli, V</creator><creator>Paulli, M</creator><creator>Borroni, RG</creator><creator>Borroni, G</creator><general>Blackwell Publishing Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>M7N</scope><scope>7X8</scope></search><sort><creationdate>200605</creationdate><title>Bilateral inguinal hernia with dislocation of great saphenous vein as complication of long‐standing granulomatous slack skin: a case report</title><author>Benedetti, M ; 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Clinically, a development of unelastic, slack skin, especially on flexural areas, is observed. Hereby, we describe a man with a 12‐year history of GSS. In 2002, for practical (limitation of movement, deambulation) and cosmetic reasons, he underwent the surgical excision of loose and sagging skinfold over inguinal area, and, afterwards, of the opposite affected inguinal skin. The surgical treatment of bilateral inguinal hernia with reposition of inguinal dislocated vasculature is also reported. In both cases the excised material confirmed the former diagnosis of GSS and revealed a very deep, muscular infiltrate of neoplastic lymphocytes. One year later, a new excision of GSS on the axillae was made. 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subjects | Dermatologic Surgical Procedures elastolysis Granuloma - complications Granuloma - pathology Granuloma - surgery hernia Hernia, Inguinal - etiology Hernia, Inguinal - pathology Hernia, Inguinal - surgery Humans interferon alpha2a life style Male Middle Aged mycosis fungoides Mycosis Fungoides - complications Mycosis Fungoides - pathology Mycosis Fungoides - surgery Recurrence Saphenous Vein - pathology Skin - pathology Skin Neoplasms - complications Skin Neoplasms - pathology Skin Neoplasms - surgery slack skin |
title | Bilateral inguinal hernia with dislocation of great saphenous vein as complication of long‐standing granulomatous slack skin: a case report |
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