Photoinduced DNA end capping via N3-methyl-5-cyanovinyl-2'-deoxyuridine

A modified oligodeoxynucleotide (ODN) containing N(3)-methyl-5-cyanovinyl-2'-deoxyuridine reacts by photoirradiation at 366 nm with an adenine residue of a complementary template ODN to yield an end-capped ODN in 87% yield.

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Bibliographic Details
Published in:Chemical communications (Cambridge, England) England), 2005-07 (25), p.3177-3179
Main Authors: Fujimoto, Kenzo, Yoshimura, Yoshinaga, Ikemoto, Tadayoshi, Nakazawa, Akio, Hayashi, Masayuki, Saito, Isao
Format: Article
Language:English
Subjects:
Base Sequence
Deoxyuridine - analogs & derivatives
Deoxyuridine - chemistry
DNA - chemistry
Photochemistry
Online Access:Get full text
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Description
Summary:A modified oligodeoxynucleotide (ODN) containing N(3)-methyl-5-cyanovinyl-2'-deoxyuridine reacts by photoirradiation at 366 nm with an adenine residue of a complementary template ODN to yield an end-capped ODN in 87% yield.
ISSN:1359-7345