Systemic Inflammatory Response Syndrome in Nosocomial Bloodstream Infections with Pseudomonas aeruginosa and Enterococcus Species: Comparison of Elderly and Nonelderly Patients

OBJECTIVES: To determine whether the systemic inflammatory response syndrome (SIRS), clinical course, and outcome of monomicrobial nosocomial bloodstream infection (BSI) due to Pseudomonas aeruginosa or Enterococcus spp. is different in elderly patients than in younger patients. DESIGN: Historical c...

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Bibliographic Details
Published in:Journal of the American Geriatrics Society (JAGS) 2006-05, Vol.54 (5), p.804-808
Main Authors: Marra, Alexandre R., Bar, Katharine, Bearman, Gonzalo M. L., Wenzel, Richard P., Edmond, Michael B.
Format: Article
Language:English
Subjects:
Age differences
Age Factors
Aged
Bacteremia - complications
Bacteremia - mortality
Bacteremia - therapy
Bacteria
Bacterial diseases
Bacterial sepsis
Biological and medical sciences
Blood
bloodstream infection
Comparative studies
Critical Care
elderly patients
Enterococcus
Enterococcus spp
Female
General aspects
Gram-Positive Bacterial Infections - complications
Gram-Positive Bacterial Infections - mortality
Gram-Positive Bacterial Infections - therapy
Hospital Mortality
Human bacterial diseases
Humans
Infections
Infectious diseases
Length of Stay
Male
Medical sciences
Middle Aged
Mortality
Older people
Outcome Assessment (Health Care)
Pseudomonas aeruginosa
Pseudomonas Infections - complications
Pseudomonas Infections - mortality
Pseudomonas Infections - therapy
SIRS
Systemic Inflammatory Response Syndrome - microbiology
Systemic Inflammatory Response Syndrome - mortality
Systemic Inflammatory Response Syndrome - therapy
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Summary:OBJECTIVES: To determine whether the systemic inflammatory response syndrome (SIRS), clinical course, and outcome of monomicrobial nosocomial bloodstream infection (BSI) due to Pseudomonas aeruginosa or Enterococcus spp. is different in elderly patients than in younger patients. DESIGN: Historical cohort study. SETTING: An 820‐bed tertiary care facility. PARTICIPANTS: One hundred twenty‐seven adults with P. aeruginosa or enterococcal BSI. MEASUREMENTS: SIRS scores were determined 2 days before the first positive blood culture through 14 days afterwards. Elderly patients (≥65, n=37) were compared with nonelderly patients (
ISSN:0002-8614
1532-5415
DOI:10.1111/j.1532-5415.2006.00698.x