Association Between Physical Activity, Physical Performance, and Inflammatory Biomarkers in an Elderly Population: The InCHIANTI Study

Background. Our aim was to determine the association between physical activity and physical performance, and inflammatory biomarkers in elderly persons. Methods. One thousand four persons aged 65 years or more, participants in a cross-sectional population-based study, were included. Interviewers col...

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Bibliographic Details
Published in:The journals of gerontology. Series A, Biological sciences and medical sciences Biological sciences and medical sciences, 2005-06, Vol.60 (6), p.760-767
Main Authors: Elosua, Roberto, Bartali, Benedetta, Ordovas, Jose M., Corsi, Anna M., Lauretani, Fulvio, Ferrucci, Luigi
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Biomarkers - blood
Blood Sedimentation
C-Reactive Protein - analysis
Cardiovascular disease
Cross-Sectional Studies
Cytokines
Female
Fibrinogen - analysis
Health
Humans
Inflammation - blood
Interleukins - blood
Interviews as Topic
Male
Motor Activity - physiology
Older people
Physical fitness
Uric Acid - blood
Walking
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Summary:Background. Our aim was to determine the association between physical activity and physical performance, and inflammatory biomarkers in elderly persons. Methods. One thousand four persons aged 65 years or more, participants in a cross-sectional population-based study, were included. Interviewers collected information on self-reported physical activity during the previous year. Moreover, 841 participants performed a 400-meter walking test to assess physical performance. Plasma concentrations of inflammatory biomarkers were determined. Results. Compared to sedentary men, men practicing light and moderate-high physical activity had a significantly lower erythrocyte sedimentation rate (−0.33 and −0.40 mm/h; p =.023 and p =.006, respectively), fibrinogen level (−43 and −39 mg/dL; p =.001 and p =.004, respectively), and logarithm of C-reactive protein (CRP) (−0.43 and −0.73 mg/L; p =.025 and p
ISSN:1079-5006
1758-535X
DOI:10.1093/gerona/60.6.760