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Parkinson's disease and dementia

Parkinson's disease (PD) is one of the most common neurodegenerative disorders, affecting about 1% of the population over the age of 60. In addition to motor abnormalities, there are several non-motor signs and symptoms that may create a considerable burden for patients and care-givers. Dementi...

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Bibliographic Details
Published in:Neurological sciences 2006-03, Vol.27 Suppl 1 (S1), p.S40-s43
Main Authors: Padovani, A, Costanzi, C, Gilberti, N, Borroni, B
Format: Article
Language:English
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Summary:Parkinson's disease (PD) is one of the most common neurodegenerative disorders, affecting about 1% of the population over the age of 60. In addition to motor abnormalities, there are several non-motor signs and symptoms that may create a considerable burden for patients and care-givers. Dementia is common and affects approximately 40% of PD patients during the course of the disease, the risk for the development of dementia being 6 times higher than in non-PD age-matched controls. In most cases, PD patients with dementia (PDD) display a dysexecutive syndrome and visuospatial deficits, while memory is relatively unaffected. The overlap between PDD and dementia with Lewy bodies suggests that they likely share similar underlying neuropathological processes.
ISSN:1590-1874
1590-3478
DOI:10.1007/s10072-006-0546-6