Improved early clinical development through human microdosing studies

Rising R&D costs and falling numbers of marketing approvals has been the subject of growing attention. To improve the overall probability of success, there is a growing positive perception within the biotechnology community that human microdosing studies could play a key role in early drug devel...

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Bibliographic Details
Published in:Drug discovery today 2005-07, Vol.10 (13), p.890-894
Main Authors: Wilding, Ian R., Bell, J. Angus
Format: Article
Language:English
Subjects:
Accelerator mass spectroscopy
ADME
Animals
Biological and medical sciences
Clinical Trials as Topic
Dose-Response Relationship, Drug
Drug Design
drug development
Drug Evaluation, Preclinical - methods
General pharmacology
Humans
Medical sciences
pharmaceutical R&D
Pharmaceutical technology. Pharmaceutical industry
pharmacokinetics
Pharmacology. Drug treatments
Technology, Pharmaceutical - economics
Technology, Pharmaceutical - methods
Technology, Pharmaceutical - trends
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Summary:Rising R&D costs and falling numbers of marketing approvals has been the subject of growing attention. To improve the overall probability of success, there is a growing positive perception within the biotechnology community that human microdosing studies could play a key role in early drug development.
ISSN:1359-6446
1878-5832
DOI:10.1016/S1359-6446(05)03509-9