HIV Superinfection

Worldwide, 16 cases of HIV-1 superinfection in humans have been reported since 2002. Superinfection is defined as the reinfection of an individual who already has an established infection with a heterologous HIV strain. Controversy exists surrounding superinfection, because it has implications conce...

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Bibliographic Details
Published in:The Journal of infectious diseases 2005-08, Vol.192 (3), p.438-444
Main Authors: Smith, Davey M., Richman, Douglas D., Little, Susan J.
Format: Article
Language:English
Subjects:
AIDS
AIDS-Related Opportunistic Infections - classification
AIDS-Related Opportunistic Infections - epidemiology
Biological and medical sciences
Coinfection
Disease progression
Fundamental and applied biological sciences. Psychology
Global Health
HIV
HIV 1
Human immunodeficiency virus 1
Humans
Infections
Infectious diseases
Medical sciences
Microbiology
Miscellaneous
Perspective
Superinfection
T lymphocytes
Vaccination
Virology
Viruses
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Summary:Worldwide, 16 cases of HIV-1 superinfection in humans have been reported since 2002. Superinfection is defined as the reinfection of an individual who already has an established infection with a heterologous HIV strain. Controversy exists surrounding superinfection, because it has implications concerning our understanding of worldwide HIV diversity, individual immunity and disease progression, and vaccine development. Here, we review the current understanding of HIV superinfection
ISSN:0022-1899
1537-6613
DOI:10.1086/431682