Borderline lepromatous leprosy presenting as a single cutaneous plaque

SUMMARY A 38‐year‐old Indonesian man presented with a single anaesthetic plaque on his right forearm and no other sensory changes. His clinical presentation was consistent with tuberculoid leprosy, but histopathology of a skin biopsy from the lesion showed borderline lepromatous disease. The patient...

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Bibliographic Details
Published in:Australasian journal of dermatology 2005-08, Vol.46 (3), p.181-183
Main Authors: Armour, Katherine S, Scolyer, Richard A, Barnetson, Ross StC
Format: Article
Language:English
Subjects:
Administration, Oral
Adult
Bacterial diseases
Biological and medical sciences
Clofazimine - administration & dosage
Dapsone - administration & dosage
Dermatology
Drug Therapy, Combination
Forearm
General aspects
Glucocorticoids - administration & dosage
Human bacterial diseases
Humans
Infectious diseases
Leprostatic Agents - administration & dosage
Leprosy
Leprosy, Borderline - diagnosis
Leprosy, Borderline - drug therapy
Leprosy, Lepromatous - diagnosis
Leprosy, Lepromatous - drug therapy
Male
Medical sciences
multidrug therapy
Prednisone - administration & dosage
Recurrence
reversal reaction
Rifampin - administration & dosage
Skin - pathology
Treatment Outcome
Tropical bacterial diseases
type 1 reaction
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Summary:SUMMARY A 38‐year‐old Indonesian man presented with a single anaesthetic plaque on his right forearm and no other sensory changes. His clinical presentation was consistent with tuberculoid leprosy, but histopathology of a skin biopsy from the lesion showed borderline lepromatous disease. The patient was treated with multidrug therapy for multibacillary disease. Seven months after initiation of treatment his solitary skin anaesthetic plaque became tumid, and he developed multiple small plaques on his arms, legs and face, without evident neuritis. He was clearly in a reversal reaction (type 1), which slowly resolved with treatment of prednisone.
ISSN:0004-8380
1440-0960
DOI:10.1111/j.1440-0960.2005.00175.x