An objective assessment of demography of gallbladder cancer

Background and Objectives Gallbladder cancer (GBC) is a lethal disease with a wide geographical, ethnic, and cultural variation suggesting major environmental influences such as diet and life style factors in the development of disease. An objective assessment of demographic profile and full implica...

Full description

Saved in:
Bibliographic Details
Published in:Journal of surgical oncology 2006-06, Vol.93 (8), p.610-614
Main Authors: Kumar, J. Ram, Tewari, Mallika, Rai, Arundhati, Sinha, Rohan, Mohapatra, Sadhu C., Shukla, Hari S.
Format: Article
Language:English
Subjects:
Adult
Aged
Case-Control Studies
Demography
Diet
Female
gallbladder cancer
gallbladder disease
Gallbladder Neoplasms - epidemiology
Gallbladder Neoplasms - genetics
Gallstones - epidemiology
Gallstones - genetics
Humans
India - epidemiology
Life Style
Male
Middle Aged
parity
Predictive Value of Tests
Retrospective Studies
Risk
Rural Health
Sex Factors
Socioeconomic Factors
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Background and Objectives Gallbladder cancer (GBC) is a lethal disease with a wide geographical, ethnic, and cultural variation suggesting major environmental influences such as diet and life style factors in the development of disease. An objective assessment of demographic profile and full implication of these features to recognize the population at risk is needed. This study was therefore undertaken to study the demography of GBC in Varanasi. Methods A retrospective study as a case—control model comprised 328 cases of GBC and 328 controls with gallstone disease (GSD). The relevant demographic data were collected and analyzed for identification of independent significant features and for the risk of GBC based on these features by calculating odds ratio. Results and Conclusions GBC predominantly a disease of females belonged to fourth and fifth decade of life. Among 328 cases of GBC only 75 were male and 253 female (M:F = 1:3.37). Majority of GBC patients were above 40 years and multiparous females. Family history of GBC was higher in GBC patients. Majority of GBC patients were of low socioeconomic status and hailed from rural background. This group tends to consume open mustard oil and water from hand pump. This study emphasizes the usefulness of demographic evaluation in diagnosis of GBC and a systematic approach to assessment of demographic features of GBC is recommended. J. Surg. Oncol. 2006;93:610–614. © 2006 Wiley‐Liss, Inc.
ISSN:0022-4790
1096-9098
DOI:10.1002/jso.20526