The effect of cognitive behavioral treatment on the positive symptoms of schizophrenia spectrum disorders: A meta-analysis

Despite the effectiveness of anti-psychotic pharmacotherapy, residual hallucinations and delusions do not completely resolve in some medicated patients. Additional cognitive behavioral therapy (CBT) seems to improve the management of positive symptoms. Despite promising results, the efficacy of CBT...

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Bibliographic Details
Published in:Schizophrenia research 2005-09, Vol.77 (1), p.1-9
Main Authors: Zimmermann, G., Favrod, J., Trieu, V.H., Pomini, V.
Format: Article
Language:English
Subjects:
Adult
Adult and adolescent clinical studies
Behavior therapy. Cognitive therapy
Biological and medical sciences
Cognitive behavioral therapy
Cognitive Therapy - methods
Combined Modality Therapy
Female
Follow-Up Studies
Humans
Male
Medical sciences
Meta-analysis
Positive symptoms
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
Psychoses
Randomized Controlled Trials as Topic
Retrospective Studies
Schizophrenia
Schizophrenia - therapy
Schizophrenic Psychology
Treatment Outcome
Treatments
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Summary:Despite the effectiveness of anti-psychotic pharmacotherapy, residual hallucinations and delusions do not completely resolve in some medicated patients. Additional cognitive behavioral therapy (CBT) seems to improve the management of positive symptoms. Despite promising results, the efficacy of CBT is still unclear. The present study addresses this issue taking into account a number of newly published controlled studies. Fourteen studies including 1484 patients, published between 1990 and 2004 were identified and a meta-analysis of their results performed. Compared to other adjunctive measures, CBT showed significant reduction in positive symptoms and there was a higher benefit of CBT for patients suffering an acute psychotic episode versus the chronic condition (effect size of 0.57 vs. 0.27). CBT is a promising adjunctive treatment for positive symptoms in schizophrenia spectrum disorders. However, a number of potentially modifying variables have not yet been examined, such as therapeutic alliance and neuropsychological deficits.
ISSN:0920-9964
1573-2509
DOI:10.1016/j.schres.2005.02.018