The diagnostic value of image guided percutaneous fine needle aspiration biopsy in equivocal mediastinal masses

The aim of this study was to assess the diagnostic value of image guided percutaneous fine needle aspiration (FNA) biopsy in equivocal mediastinal masses. Sixty-six patients with an equivocal mediastinal mass who underwent FNA biopsy between 1993 and 2003 were eligible for final analysis. The cytolo...

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Bibliographic Details
Published in:Langenbeck's archives of surgery 2006-06, Vol.391 (3), p.222-227
Main Authors: Güllüoğlu, Mine G, Kiliçaslan, Zeki, Toker, Alper, Kalayci, Göksel, Yilmazbayhan, Dilek
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Biopsy, Fine-Needle - methods
Child
Child, Preschool
Diagnosis, Differential
Female
Humans
Male
Mediastinal Diseases - diagnosis
Middle Aged
Predictive Value of Tests
Radiography, Interventional
Retrospective Studies
Sensitivity and Specificity
Tomography, X-Ray Computed
Ultrasonography, Interventional
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Summary:The aim of this study was to assess the diagnostic value of image guided percutaneous fine needle aspiration (FNA) biopsy in equivocal mediastinal masses. Sixty-six patients with an equivocal mediastinal mass who underwent FNA biopsy between 1993 and 2003 were eligible for final analysis. The cytological and definitive diagnosis of masses were grouped as primary 22 (33%)-30 (46%) and secondary (metastatic) neoplasms 18 (27%)-18 (27%) and nonneoplastic lesions 20 (30%)-18 (27%) respectively. The diagnostic accuracy (95% C.I.) of FNA biopsy for primary mediastinal neoplasms, secondary neoplasms and nonneoplastic lesions were found to be 93.3 (83.8-98.2)%, 100 (95.1-100)%, 93.3 (83.8-98.2)%, respectively. Image guided percutaneous FNA biopsy is a safe and highly accurate diagnostic method for equivocal mediastinal masses.
ISSN:1435-2443
1435-2451
DOI:10.1007/s00423-006-0029-5