Spinal granulocytic sarcoma (chloroma) presenting as acute cord compression in a nonleukemic patient

The case of a previously healthy 24-year-old man diagnosed with extradural thoracic granulocytic sarcoma with no evidence of bone marrow or other hematological involvement is described. The tumor was removed totally by microsurgery. The histopathological examination was consistent with granulocytic...

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Bibliographic Details
Published in:Neurology India 2005-04, Vol.53 (2), p.221-223
Main Authors: Kalayci, Murat, Sümer, Murat, Yenidünya, Sibel, Ozdolap, Senay, Açikgöz, Bektas
Format: Article
Language:English
Subjects:
Adult
Antimitotic agents
Antineoplastic agents
Case studies
Decompression, Surgical
Diagnosis
Dosage and administration
Drug therapy
Humans
Leukemia
Magnetic Resonance Imaging
Male
Sarcoma
Sarcoma, Myeloid - complications
Sarcoma, Myeloid - pathology
Sarcoma, Myeloid - surgery
Spinal Cord Compression - etiology
Spinal Cord Compression - pathology
Spinal Cord Compression - surgery
Spinal Cord Neoplasms - complications
Spinal Cord Neoplasms - pathology
Spinal Cord Neoplasms - surgery
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Description
Summary:The case of a previously healthy 24-year-old man diagnosed with extradural thoracic granulocytic sarcoma with no evidence of bone marrow or other hematological involvement is described. The tumor was removed totally by microsurgery. The histopathological examination was consistent with granulocytic sarcoma. Granulocytic sarcomas are most commonly found in the context of an acute myelogenous leukemia or in chronic myelogenous leukemia. They rarely have been reported in otherwise healthy patients without any evidence of systemic disease. A review of the literature revealed only 14 more nonleukaemic cases with granulocytic sarcoma causing thoracic spinal cord compression.
ISSN:0028-3886
1998-4022
DOI:10.4103/0028-3886.16418