Feasibility of a mass vaccination campaign using a two-dose oral cholera vaccine in an urban cholera-endemic setting in Mozambique

We conducted a study to assess the feasibility and the potential vaccine coverage of a mass vaccination campaign using a two-dose oral cholera vaccine in an urban endemic neighbourhood of Beira, Mozambique. The campaign was conducted from December 2003 to January 2004. Overall 98,152 doses were admi...

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Bibliographic Details
Published in:Vaccine 2006-05, Vol.24 (22), p.4890-4895
Main Authors: Cavailler, Philippe, Lucas, Marcelino, Perroud, Valerie, McChesney, Margaret, Ampuero, Sonia, Guérin, Philippe J., Legros, Dominique, Nierle, Thomas, Mahoudeau, Claude, Lab, Bruno, Kahozi, Pierre, Deen, Jacqueline L., von Seidlein, Lorenz, Wang, Xuan-Yi, Puri, Mahesh, Ali, Mohammad, Clemens, John D., Songane, Francisco, Baptista, Alberto, Ismael, Fauzia, Barreto, Avertino, Chaignat, Claire-Lise
Format: Article
Language:English
Subjects:
Administration, Oral
Adolescent
Applied microbiology
Bacterial diseases
Bacteriology
Biological and medical sciences
Child
Child, Preschool
Cholera
Cholera - epidemiology
Cholera - prevention & control
Cost
Costs and Cost Analysis
Female
Fundamental and applied biological sciences. Psychology
Human bacterial diseases
Humans
Immunization
Infectious diseases
Male
Mass Vaccination - economics
Mass-vaccination
Medical sciences
Microbiology
Miscellaneous
Mozambique
Mozambique - epidemiology
Public health
Smallpox
Tropical bacterial diseases
Vaccines
Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects)
Vibrio cholerae
Waterborne diseases
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Description
Summary:We conducted a study to assess the feasibility and the potential vaccine coverage of a mass vaccination campaign using a two-dose oral cholera vaccine in an urban endemic neighbourhood of Beira, Mozambique. The campaign was conducted from December 2003 to January 2004. Overall 98,152 doses were administered, and vaccine coverage of the target population was 58.6% and 53.6% for the first and second rounds, respectively. The direct cost of the campaign, which excludes the price of the vaccine, amounted to slightly over $90,000, resulting in the cost per fully vaccinated person of $2.09, which is relatively high. However, in endemic settings where outbreaks are likely to occur, integrating cholera vaccination into the routine activities of the public health system could reduce such costs.
ISSN:0264-410X
1873-2518
DOI:10.1016/j.vaccine.2005.10.006