Relation of Chronic and Acute Glycemic Control on Mortality in Acute Myocardial Infarction With Diabetes Mellitus

Acute hyperglycemia during myocardial infarction predicts adverse short-term outcomes and mortality in diabetic patients. Conversely, chronic hyperglycemia is associated with an increased incidence of long-term cardiovascular complications, although its effect on acute hyperglycemic response and mor...

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Bibliographic Details
Published in:The American journal of cardiology 2005-07, Vol.96 (2), p.183-186
Main Authors: Cao, Jie J., Hudson, Michael, Jankowski, Michelle, Whitehouse, Fred, Weaver, W. Douglas
Format: Article
Language:English
Subjects:
Acute Disease
Age Distribution
Aged
Aged, 80 and over
Biological and medical sciences
Blood Glucose - analysis
Cardiology. Vascular system
Cause of Death
Chronic Disease
Cohort Studies
Confidence Intervals
Coronary heart disease
Diabetes
Diabetes. Impaired glucose tolerance
Endocrine pancreas. Apud cells (diseases)
Endocrinopathies
Etiopathogenesis. Screening. Investigations. Target tissue resistance
Female
Glucose
Heart
Heart attacks
Humans
Hyperglycemia - diagnosis
Hyperglycemia - mortality
Hyperglycemia - therapy
Incidence
Male
Medical sciences
Middle Aged
Mortality
Myocardial Infarction - diagnosis
Myocardial Infarction - mortality
Myocardial Infarction - therapy
Myocarditis. Cardiomyopathies
Predictive Value of Tests
Probability
Prognosis
Retrospective Studies
Risk Assessment
Severity of Illness Index
Sex Distribution
Survival Analysis
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Description
Summary:Acute hyperglycemia during myocardial infarction predicts adverse short-term outcomes and mortality in diabetic patients. Conversely, chronic hyperglycemia is associated with an increased incidence of long-term cardiovascular complications, although its effect on acute hyperglycemic response and mortality after acute myocardial infarction is unknown. We investigated the prognostic relation of the glucose concentration at admission and the baseline average glycohemoglobin on acute myocardial infarction mortality. Of 808 consecutive diabetic patients with acute myocardial infarction, the most significant independent predictor of in-hospital mortality was the glucose concentration at admission. Baseline glycohemoglobin strongly correlated with admission hyperglycemia but did not predict mortality independently.
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2005.03.040