Correlation of Magnetic Resonance Imaging Findings with Hexamethylpropyleneamine Oxime Brain Single Photon Emission Computed Tomography in Ischemic Stroke Patients in the Subacute Stage

Purpose: To evaluate the correlation between magnetic resonance imaging (MRI) findings and 99mTc-hexamethylpropyleneamine oxime (HMPAO) brain single photon emission computed tomography (SPECT) during the subacute stage in ischemic stroke patients. Material and Methods: The T1 and T2-weighted images...

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Bibliographic Details
Published in:Acta radiologica (1987) 2006-05, Vol.47 (4), p.401-407
Main Authors: Kire i, D., Ta tekin, G., Cengiz, . L., Üstün, M. E., Yürüten, B.
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Biological and medical sciences
Brain - diagnostic imaging
Brain Ischemia - diagnosis
Brain Ischemia - etiology
Female
Humans
Magnetic Resonance Imaging - methods
Male
Medical sciences
Middle Aged
Neurology
Oximes
Perfusion
Radiopharmaceuticals
Severity of Illness Index
Stroke - diagnosis
Stroke - etiology
Tomography, Emission-Computed, Single-Photon - methods
Vascular diseases and vascular malformations of the nervous system
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Summary:Purpose: To evaluate the correlation between magnetic resonance imaging (MRI) findings and 99mTc-hexamethylpropyleneamine oxime (HMPAO) brain single photon emission computed tomography (SPECT) during the subacute stage in ischemic stroke patients. Material and Methods: The T1 and T2-weighted images and brain SPECT findings of 84 patients (mean age 60.69±12.47 years) with subacute cerebral ischemia during the period 1998-2004 were reviewed. All HMPAO SPECT and MRI studies were performed between 3 and 7 days (mean time delay 4.76±1.29 days) after the onset of stroke symptoms. Results: An ischemic lesion was seen both in T1 and T2-weighted images with perfusion defects above 60% (severe defect) according to count pixel data of the lesion in HMPAO SPECT studies in 30 (90.9%) of 33 patients. Otherwise, the ischemic lesion was seen only on T2-weighted images with perfusion defects between 30% and 60% (moderate defect) in HMPAO SPECT studies in 25 (89.3%) of 28 patients. In 20 (87%) of 23 patients who had perfusion defects below 30% (mild defect) on HMPAO SPECT, only non-specific findings such as cerebral atrophy and or periventricular ischemic-gliotic lesions could be seen in MRI. The difference between these ratios was statistically significant (P
ISSN:0284-1851
1600-0455
DOI:10.1080/02841850600570490