Prognostic utility of a semiquantitative spinal deformity index

• Published in: Bone (New York, N.Y.) N.Y.), 2005-08, Vol.37 (2), p.175-179
• Main Authors: Crans, Gerald G., Genant, Harry K., Krege, John H.
• Format: Article
• Language: English
• Subjects: Aged; Biological and medical sciences; Diseases of the osteoarticular system; Female; Follow-Up Studies; Humans; Injuries of the limb. Injuries of the spine; Logistic Models; Medical sciences; Middle Aged; Osteoporosis; Osteoporosis, Postmenopausal - complications; Osteoporosis. Osteomalacia. Paget disease; Prognosis; Risk Assessment; Severity of Illness Index; Spinal deformity index; Spinal Fractures - diagnosis; Spinal Fractures - etiology; Spinal Fractures - pathology; Traumas. Diseases due to physical agents; Vertebral fracture
• ISSN: 8756-3282; 1873-2763
• DOI: 10.1016/j.bone.2005.04.003

The semiquantitative spinal deformity index (SDI) is a summary measure of the vertebral fracture status of the spine incorporating both the number and severity of vertebral fractures. For each vertebra, a visual semiquantitative grade of 0, 1, 2, or 3 is assigned for no fracture or mild, moderate, or severe fracture, respectively, and the SDI is calculated by summing the fracture grades of all vertebrae (T4 to L4). We investigated the effect of prevalent vertebral fracture number and severity, as integrated by the SDI, on 3-year vertebral fracture risk by performing logistic regression modeling with data from the MORE trial. There was a striking linear relationship between baseline SDI and the model-based vertebral fracture risk estimates, with a near-perfect correlation ( r = 0.98, P