Effect of Tamarindus indica fruits on blood pressure and lipid-profile in human model: an in vivo approach

Fruits of Tamarindus indica were evaluated for their effects on lipid profile, systolic and diastolic blood pressure and body weight in human subjects. Dried and pulverized pulp of T. indica fruits, at a dose of 15 mg/kg body weight, was found to reduce total cholesterol level (p = 0.031) and LDL-ch...

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Bibliographic Details
Published in:Pakistan journal of pharmaceutical sciences 2006-04, Vol.19 (2), p.125-129
Main Authors: Iftekhar, A S M Maruf, Rayhan, Israt, Quadir, Mohiuddin Abdul, Akhteruzzaman, Sharif, Hasnat, Abul
Format: Article
Language:English
Subjects:
Administration, Oral
Adult
Blood Pressure - drug effects
Cholesterol - blood
Cholesterol, LDL - blood
Female
Fruit
Humans
Lipid Metabolism - drug effects
Male
Middle Aged
Plant Extracts - administration & dosage
Plant Extracts - pharmacology
Tamarindus
Triglycerides - blood
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Summary:Fruits of Tamarindus indica were evaluated for their effects on lipid profile, systolic and diastolic blood pressure and body weight in human subjects. Dried and pulverized pulp of T. indica fruits, at a dose of 15 mg/kg body weight, was found to reduce total cholesterol level (p = 0.031) and LDL-cholesterol level (p = 0.004) to a significant extent. Though the fruits exerted no conspicuous effect on body weight and systolic blood pressure, it significantly reduced the diastolic pressure as confirmed by independent sample t-test at 5% significance level.
ISSN:1011-601X