Effect of active fraction of cerebral on expression of caspase-3 and beta-amyloid precursor protein during therapy of hemorrhagic stroke in the acute and delayed periods

Active anti-stroke fraction of Cerebral preparation (extract of water-soluble molecules from brain tissue of animals with hemorrhagic stroke) decreased caspase-3 expression and improved survival of experimental animals in the acute period after hemorrhagic stroke.

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Bibliographic Details
Published in:Bulletin of experimental biology and medicine 2005-02, Vol.139 (2), p.207-209
Main Authors: Makarenko, A N, Vasil'eva, I G, Chopik, N G, Galanta, E S, Tsyubko, O I, Oleksenko, N P
Format: Article
Language:English
Subjects:
Acute Disease
Amyloid beta-Protein Precursor - antagonists & inhibitors
Amyloid beta-Protein Precursor - genetics
Amyloid beta-Protein Precursor - metabolism
Animals
Caspase 3
Caspase Inhibitors
Caspases - genetics
Caspases - metabolism
Cerebral Hemorrhage - drug therapy
Cerebral Hemorrhage - enzymology
Cerebral Hemorrhage - metabolism
Male
Rats
RNA, Messenger - analysis
RNA, Messenger - metabolism
Stroke - drug therapy
Stroke - enzymology
Stroke - metabolism
Tissue Extracts - pharmacology
Tissue Extracts - therapeutic use
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Description
Summary:Active anti-stroke fraction of Cerebral preparation (extract of water-soluble molecules from brain tissue of animals with hemorrhagic stroke) decreased caspase-3 expression and improved survival of experimental animals in the acute period after hemorrhagic stroke.
ISSN:0007-4888
1573-8221
DOI:10.1007/s10517-005-0249-7