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Subtypes of peripheral adenocarcinoma of the lung: differentiation by thin-section CT
The purpose of this study was to scrutinize morphological characteristics of thin-section CT of the histopathological subtypes of adenocarcinoma of the lung. The subjects consisted of 83 patients with 87 adenocarcinomas measuring 3 cm or less in the largest. The tumors were divided into three groups...
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Published in: | European radiology 2005-08, Vol.15 (8), p.1563-1568 |
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description | The purpose of this study was to scrutinize morphological characteristics of thin-section CT of the histopathological subtypes of adenocarcinoma of the lung. The subjects consisted of 83 patients with 87 adenocarcinomas measuring 3 cm or less in the largest. The tumors were divided into three groups (group I: Noguchi's histological subtypes type A and B tumors, group II: type C tumors, and group III: type D, E, and F tumors). In each group, tumor size, shape (round versus polygonal), presence of air bronchogram, bubble-like areas, coarse spiculation, pleural tag, and ratio of ground glass attenuation (GGA) were evaluated. Most of the group II lesions showed polygonal shape, whereas tumors in other groups were round in shape (P |
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The subjects consisted of 83 patients with 87 adenocarcinomas measuring 3 cm or less in the largest. The tumors were divided into three groups (group I: Noguchi's histological subtypes type A and B tumors, group II: type C tumors, and group III: type D, E, and F tumors). In each group, tumor size, shape (round versus polygonal), presence of air bronchogram, bubble-like areas, coarse spiculation, pleural tag, and ratio of ground glass attenuation (GGA) were evaluated. Most of the group II lesions showed polygonal shape, whereas tumors in other groups were round in shape (P<0.01). Air bronchogram and bubble-like areas of low attenuation was seen more frequently in group II compared with those in group III (P<0.01). GGA areas were largest in group I and smallest in group III (P<0.01). We believe thin-section CT findings reflect the histopathological subtypes of adenocarcinoma of the lung. The presence of air bronchogram and bubble-like areas of low attenuation areas in particular is useful to differentiate replacement growth tumors from non-replacement growth tumors.</description><identifier>ISSN: 0938-7994</identifier><identifier>EISSN: 1432-1084</identifier><identifier>DOI: 10.1007/s00330-004-2595-7</identifier><identifier>PMID: 15846496</identifier><language>eng</language><publisher>Germany: Springer Nature B.V</publisher><subject>Adenocarcinoma ; Adenocarcinoma - classification ; Adenocarcinoma - diagnostic imaging ; Aged ; Attenuation ; Cancer ; Female ; Humans ; Lung - diagnostic imaging ; Lung - pathology ; Lung Neoplasms - classification ; Lung Neoplasms - diagnostic imaging ; Lungs ; Male ; Physical characteristics ; Polygons ; Tomography, X-Ray Computed - methods ; Tumors</subject><ispartof>European radiology, 2005-08, Vol.15 (8), p.1563-1568</ispartof><rights>Springer-Verlag 2005.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c393t-c9a39a126a1ff6d3cbdbe6e03424d37fa6ccf3fe0e8114007559288c9f4bd783</citedby><cites>FETCH-LOGICAL-c393t-c9a39a126a1ff6d3cbdbe6e03424d37fa6ccf3fe0e8114007559288c9f4bd783</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15846496$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Nakazono, T</creatorcontrib><creatorcontrib>Sakao, Y</creatorcontrib><creatorcontrib>Yamaguchi, K</creatorcontrib><creatorcontrib>Imai, S</creatorcontrib><creatorcontrib>Kumazoe, H</creatorcontrib><creatorcontrib>Kudo, S</creatorcontrib><title>Subtypes of peripheral adenocarcinoma of the lung: differentiation by thin-section CT</title><title>European radiology</title><addtitle>Eur Radiol</addtitle><description>The purpose of this study was to scrutinize morphological characteristics of thin-section CT of the histopathological subtypes of adenocarcinoma of the lung. The subjects consisted of 83 patients with 87 adenocarcinomas measuring 3 cm or less in the largest. The tumors were divided into three groups (group I: Noguchi's histological subtypes type A and B tumors, group II: type C tumors, and group III: type D, E, and F tumors). In each group, tumor size, shape (round versus polygonal), presence of air bronchogram, bubble-like areas, coarse spiculation, pleural tag, and ratio of ground glass attenuation (GGA) were evaluated. Most of the group II lesions showed polygonal shape, whereas tumors in other groups were round in shape (P<0.01). Air bronchogram and bubble-like areas of low attenuation was seen more frequently in group II compared with those in group III (P<0.01). GGA areas were largest in group I and smallest in group III (P<0.01). We believe thin-section CT findings reflect the histopathological subtypes of adenocarcinoma of the lung. The presence of air bronchogram and bubble-like areas of low attenuation areas in particular is useful to differentiate replacement growth tumors from non-replacement growth tumors.</description><subject>Adenocarcinoma</subject><subject>Adenocarcinoma - classification</subject><subject>Adenocarcinoma - diagnostic imaging</subject><subject>Aged</subject><subject>Attenuation</subject><subject>Cancer</subject><subject>Female</subject><subject>Humans</subject><subject>Lung - diagnostic imaging</subject><subject>Lung - pathology</subject><subject>Lung Neoplasms - classification</subject><subject>Lung Neoplasms - diagnostic imaging</subject><subject>Lungs</subject><subject>Male</subject><subject>Physical characteristics</subject><subject>Polygons</subject><subject>Tomography, X-Ray Computed - methods</subject><subject>Tumors</subject><issn>0938-7994</issn><issn>1432-1084</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><recordid>eNpdkE9LxDAQxYMouq5-AC9SELxFJ03aJN5k8R8seHA9hzSduF26bU3aw357W3dB8DQM782bmR8hVwzuGIC8jwCcAwUQNM10RuURmTHBU8pAiWMyA80VlVqLM3Ie4wYANBPylJyxTIlc6HxGPj-Got91GJPWJx2GqltjsHViS2xaZ4OrmnZrJ7FfY1IPzddDUlbeY8Cmr2xftU1S7EaxamhE99svVhfkxNs64uWhzsnq-Wm1eKXL95e3xeOSOq55T522XFuW5pZ5n5fcFWWBOQIXqSi59DZ3znOPgIoxMX6cZTpVymkvilIqPie3-9gutN8Dxt5sq-iwrm2D7RBNriBToORovPln3LRDaMbTDB_XK6GkzEcX27tcaGMM6E0Xqq0NO8PATMDNHrgZgZsJuJmSrw_JQ7HF8m_iQJj_AMJJe7U</recordid><startdate>20050801</startdate><enddate>20050801</enddate><creator>Nakazono, T</creator><creator>Sakao, Y</creator><creator>Yamaguchi, K</creator><creator>Imai, S</creator><creator>Kumazoe, H</creator><creator>Kudo, S</creator><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QO</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7P</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20050801</creationdate><title>Subtypes of peripheral adenocarcinoma of the lung: differentiation by thin-section CT</title><author>Nakazono, T ; 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The subjects consisted of 83 patients with 87 adenocarcinomas measuring 3 cm or less in the largest. The tumors were divided into three groups (group I: Noguchi's histological subtypes type A and B tumors, group II: type C tumors, and group III: type D, E, and F tumors). In each group, tumor size, shape (round versus polygonal), presence of air bronchogram, bubble-like areas, coarse spiculation, pleural tag, and ratio of ground glass attenuation (GGA) were evaluated. Most of the group II lesions showed polygonal shape, whereas tumors in other groups were round in shape (P<0.01). Air bronchogram and bubble-like areas of low attenuation was seen more frequently in group II compared with those in group III (P<0.01). GGA areas were largest in group I and smallest in group III (P<0.01). We believe thin-section CT findings reflect the histopathological subtypes of adenocarcinoma of the lung. The presence of air bronchogram and bubble-like areas of low attenuation areas in particular is useful to differentiate replacement growth tumors from non-replacement growth tumors.</abstract><cop>Germany</cop><pub>Springer Nature B.V</pub><pmid>15846496</pmid><doi>10.1007/s00330-004-2595-7</doi><tpages>6</tpages></addata></record> |
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subjects | Adenocarcinoma Adenocarcinoma - classification Adenocarcinoma - diagnostic imaging Aged Attenuation Cancer Female Humans Lung - diagnostic imaging Lung - pathology Lung Neoplasms - classification Lung Neoplasms - diagnostic imaging Lungs Male Physical characteristics Polygons Tomography, X-Ray Computed - methods Tumors |
title | Subtypes of peripheral adenocarcinoma of the lung: differentiation by thin-section CT |
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