Right-sided diaphragmatic hernia in infants after liver transplantation

• Published in: Journal of pediatric surgery 2005-07, Vol.40 (7), p.1181-1184
• Main Authors: McCabe, Amanda J., Orr, John D., Sharif, Khalid, de Ville de Goyet, Jean
• Format: Article
• Language: English
• Subjects: Body Weight; Female; Functional Laterality; Hernia, Diaphragmatic - etiology; Humans; Infant; Liver Transplantation; Male; Postoperative Complications; Risk Factors
• ISSN: 0022-3468; 1531-5037
• DOI: 10.1016/j.jpedsurg.2005.03.063

Liver transplantation is just as successful in infants as in older children, but more challenging. This relates to the low weight of the recipients and to their rapidly deteriorating clinical condition (malnutrition and end-stage liver disease) ( J Pediatr 1990;117:205-210; BMJ 1993;307:825-828; Ann Surg 1996;223:658-664; Transplantation 1997;64:242-248; J Pediatr Surg 1998;33:20-23). In addition, higher rates of diaphragmatic complications have been shown to significantly correlate with a younger age ( Transplantation 2002;73:228-232; Transpl Int 1998;11:281-283; Pediatr Transplant 2000;4:39-44), but diaphragmatic hernia has never been reported as a complication of liver transplantation. In this report, 2 patients who developed diaphragmatic hernia after liver transplantation are presented. The possible role of several contributing factors resulting in diaphragmatic hernia is discussed. These factors include (1) diaphragm thinness related to low weight and malnutrition, (2) direct trauma at operation (dissection and diathermy), (3) increased abdominal pressure after transplantation caused by the use of a slightly oversized liver graft, and (4) the medial positioning of the partial liver graft in the abdomen.