The effects of oxytocin on the activity of cells in the anterior hypothalamus in experimental stress

Acute experiments on white laboratory rats were performed to study spike activity in neurons of the anterior hypothalamus in response to i.v. injections of different doses of oxytocin. The results showed that oxytocin evoked different types of rearrangement of neuron activity both in intact and in s...

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Bibliographic Details
Published in:Neuroscience and behavioral physiology 2005-06, Vol.35 (5), p.469-471
Main Authors: Mukhitdinova, Kh N, Stamova, L G, Rasulov, M M
Format: Article
Language:English
Subjects:
Action Potentials - drug effects
Animals
Dose-Response Relationship, Drug
Female
Hypothalamus - cytology
Neurons - drug effects
Nonlinear Dynamics
Oxytocin - pharmacology
Rats
Reaction Time - drug effects
Stress, Physiological - physiopathology
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Summary:Acute experiments on white laboratory rats were performed to study spike activity in neurons of the anterior hypothalamus in response to i.v. injections of different doses of oxytocin. The results showed that oxytocin evoked different types of rearrangement of neuron activity both in intact and in stressed animals. The dose-related effects of oxytocin affected the latent periods of neuron responses and the nature of rearrangements in spike activity. The greater the frequency of the baseline activity of the cells, the less marked was the response of the neurons to administration of oxytocin.
ISSN:0097-0549
1573-899X
DOI:10.1007/s11055-005-0081-6