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Age‐specific reference levels of serum prostate‐specific antigen and prostate volume in healthy Arab men
OBJECTIVE To determine age‐specific reference ranges for serum prostate‐specific antigen (PSA) concentration and prostate volumes in a population of healthy Arab men. SUBJECTS AND METHODS Blood samples were taken from 396 healthy Arab men (from Kuwait and Oman) aged 15–79 years and from across the s...
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| Published in: | BJU international 2005-08, Vol.96 (3), p.308-312 |
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| Main Authors: | , , , , , , , |
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| cites | cdi_FETCH-LOGICAL-c3970-cf4c0dbb5c1efbf857eae5be811e7d9bf711f8ae8e18a66fa2615aa8a5f6d4313 |
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| container_title | BJU international |
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| creator | Kehinde, Elijah O. Mojiminiyi, Olusegun A. Sheikh, Mehraj Al‐Awadi, Kaleel A. Daar, Abdallah S. Al‐Hunayan, Adel Anim, Jehoram T. Al‐Sumait, Aisha A. |
| description | OBJECTIVE
To determine age‐specific reference ranges for serum prostate‐specific antigen (PSA) concentration and prostate volumes in a population of healthy Arab men.
SUBJECTS AND METHODS
Blood samples were taken from 396 healthy Arab men (from Kuwait and Oman) aged 15–79 years and from across the social spectrum. Men aged >40 years had a digital rectal examination and transrectal ultrasonography of the prostate to determine prostate volume. The serum PSA level was measured using commercial kits, and age‐specific ranges for PSA levels and prostate volume determined.
RESULTS
The serum PSA ranges (ng/mL) for each age range in Arab men were: 40–49 years, 0–0.9; 60–69, 0–2.7; 70–79, 0–5.5 ng/mL; the respective prostate volumes were 8–22, 9–30 and 10–33 mL. The serum PSA level and prostate volume correlated with age (P |
| doi_str_mv | 10.1111/j.1464-410X.2005.05620.x |
| format | article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_68076556</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>68076556</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3970-cf4c0dbb5c1efbf857eae5be811e7d9bf711f8ae8e18a66fa2615aa8a5f6d4313</originalsourceid><addsrcrecordid>eNqNkEtOwzAQQC0EovyugLyBXYPdxE6yYFEqvkJiAxI7a-KMSyonLXFS2h1H4IycBIeW3w5vZuR5Mx4_QihnAffnZBLwSEb9iLPHYMCYCJiQAxYsNsjOd2HzK2ep7JFd5yaM-QsptkmPSxYNYp7uEDsc4_vrm5uhLkyhaY0Ga6w0UotztI5ODXVYtyWd1VPXQPOHhqopxlj5mH_X6Xxq2xJpUdEnBNs8LemwhoyWWO2TLQPW4cE67pGHi_P70VX_9u7yejS87eswjVlfm0izPMuE5mgyk4gYAUWGCecY52lmYs5NApggT0BKAwPJBUACwsg8Cnm4R45Xc_1Ozy26RpWF02gtVDhtnZIJi6UQ0oPJCtR-eef_rmZ1UUK9VJypzrSaqE6i6oSqzrT6NK0WvvVw_UablZj_NK7VeuBoDYDTYE0NlS7cLy6VaciE505X3EthcfnvBdTZzUOXhR9wXJ5r</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>68076556</pqid></control><display><type>article</type><title>Age‐specific reference levels of serum prostate‐specific antigen and prostate volume in healthy Arab men</title><source>Wiley</source><creator>Kehinde, Elijah O. ; Mojiminiyi, Olusegun A. ; Sheikh, Mehraj ; Al‐Awadi, Kaleel A. ; Daar, Abdallah S. ; Al‐Hunayan, Adel ; Anim, Jehoram T. ; Al‐Sumait, Aisha A.</creator><creatorcontrib>Kehinde, Elijah O. ; Mojiminiyi, Olusegun A. ; Sheikh, Mehraj ; Al‐Awadi, Kaleel A. ; Daar, Abdallah S. ; Al‐Hunayan, Adel ; Anim, Jehoram T. ; Al‐Sumait, Aisha A.</creatorcontrib><description>OBJECTIVE
To determine age‐specific reference ranges for serum prostate‐specific antigen (PSA) concentration and prostate volumes in a population of healthy Arab men.
SUBJECTS AND METHODS
Blood samples were taken from 396 healthy Arab men (from Kuwait and Oman) aged 15–79 years and from across the social spectrum. Men aged >40 years had a digital rectal examination and transrectal ultrasonography of the prostate to determine prostate volume. The serum PSA level was measured using commercial kits, and age‐specific ranges for PSA levels and prostate volume determined.
RESULTS
The serum PSA ranges (ng/mL) for each age range in Arab men were: 40–49 years, 0–0.9; 60–69, 0–2.7; 70–79, 0–5.5 ng/mL; the respective prostate volumes were 8–22, 9–30 and 10–33 mL. The serum PSA level and prostate volume correlated with age (P < 0.001). Arab men had lower serum PSA levels and prostate volumes than those reported for Caucasians, but similar to those reported for Asians (Japanese and Chinese).
CONCLUSION
These results indicate that Arab men have lower PSA levels and prostate volumes than Caucasians. The levels are slightly lower than those reported in the Japanese and, as in the Japanese, low PSA levels and small prostate volumes might be related to the low incidence of clinical prostate cancer in Arab men.</description><identifier>ISSN: 1464-4096</identifier><identifier>EISSN: 1464-410X</identifier><identifier>DOI: 10.1111/j.1464-410X.2005.05620.x</identifier><identifier>PMID: 16042719</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Science Ltd</publisher><subject>Adolescent ; Adult ; Age Factors ; Aged ; Arab ; Arabs ; Asian ; Biological and medical sciences ; Caucasian ; Genital system. Mammary gland ; Humans ; Investigative techniques, diagnostic techniques (general aspects) ; Kuwait - ethnology ; Male ; Medical sciences ; Middle Aged ; Nephrology. Urinary tract diseases ; Oman - ethnology ; Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques ; Prostate - anatomy & histology ; prostate volume ; Prostate-Specific Antigen - blood ; prostate‐specific antigen ; Prostatic Neoplasms - blood ; Prostatic Neoplasms - ethnology ; Prostatic Neoplasms - pathology ; Reference Values</subject><ispartof>BJU international, 2005-08, Vol.96 (3), p.308-312</ispartof><rights>2005 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3970-cf4c0dbb5c1efbf857eae5be811e7d9bf711f8ae8e18a66fa2615aa8a5f6d4313</citedby><cites>FETCH-LOGICAL-c3970-cf4c0dbb5c1efbf857eae5be811e7d9bf711f8ae8e18a66fa2615aa8a5f6d4313</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=16969305$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16042719$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kehinde, Elijah O.</creatorcontrib><creatorcontrib>Mojiminiyi, Olusegun A.</creatorcontrib><creatorcontrib>Sheikh, Mehraj</creatorcontrib><creatorcontrib>Al‐Awadi, Kaleel A.</creatorcontrib><creatorcontrib>Daar, Abdallah S.</creatorcontrib><creatorcontrib>Al‐Hunayan, Adel</creatorcontrib><creatorcontrib>Anim, Jehoram T.</creatorcontrib><creatorcontrib>Al‐Sumait, Aisha A.</creatorcontrib><title>Age‐specific reference levels of serum prostate‐specific antigen and prostate volume in healthy Arab men</title><title>BJU international</title><addtitle>BJU Int</addtitle><description>OBJECTIVE
To determine age‐specific reference ranges for serum prostate‐specific antigen (PSA) concentration and prostate volumes in a population of healthy Arab men.
SUBJECTS AND METHODS
Blood samples were taken from 396 healthy Arab men (from Kuwait and Oman) aged 15–79 years and from across the social spectrum. Men aged >40 years had a digital rectal examination and transrectal ultrasonography of the prostate to determine prostate volume. The serum PSA level was measured using commercial kits, and age‐specific ranges for PSA levels and prostate volume determined.
RESULTS
The serum PSA ranges (ng/mL) for each age range in Arab men were: 40–49 years, 0–0.9; 60–69, 0–2.7; 70–79, 0–5.5 ng/mL; the respective prostate volumes were 8–22, 9–30 and 10–33 mL. The serum PSA level and prostate volume correlated with age (P < 0.001). Arab men had lower serum PSA levels and prostate volumes than those reported for Caucasians, but similar to those reported for Asians (Japanese and Chinese).
CONCLUSION
These results indicate that Arab men have lower PSA levels and prostate volumes than Caucasians. The levels are slightly lower than those reported in the Japanese and, as in the Japanese, low PSA levels and small prostate volumes might be related to the low incidence of clinical prostate cancer in Arab men.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Age Factors</subject><subject>Aged</subject><subject>Arab</subject><subject>Arabs</subject><subject>Asian</subject><subject>Biological and medical sciences</subject><subject>Caucasian</subject><subject>Genital system. Mammary gland</subject><subject>Humans</subject><subject>Investigative techniques, diagnostic techniques (general aspects)</subject><subject>Kuwait - ethnology</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Nephrology. Urinary tract diseases</subject><subject>Oman - ethnology</subject><subject>Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques</subject><subject>Prostate - anatomy & histology</subject><subject>prostate volume</subject><subject>Prostate-Specific Antigen - blood</subject><subject>prostate‐specific antigen</subject><subject>Prostatic Neoplasms - blood</subject><subject>Prostatic Neoplasms - ethnology</subject><subject>Prostatic Neoplasms - pathology</subject><subject>Reference Values</subject><issn>1464-4096</issn><issn>1464-410X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><recordid>eNqNkEtOwzAQQC0EovyugLyBXYPdxE6yYFEqvkJiAxI7a-KMSyonLXFS2h1H4IycBIeW3w5vZuR5Mx4_QihnAffnZBLwSEb9iLPHYMCYCJiQAxYsNsjOd2HzK2ep7JFd5yaM-QsptkmPSxYNYp7uEDsc4_vrm5uhLkyhaY0Ga6w0UotztI5ODXVYtyWd1VPXQPOHhqopxlj5mH_X6Xxq2xJpUdEnBNs8LemwhoyWWO2TLQPW4cE67pGHi_P70VX_9u7yejS87eswjVlfm0izPMuE5mgyk4gYAUWGCecY52lmYs5NApggT0BKAwPJBUACwsg8Cnm4R45Xc_1Ozy26RpWF02gtVDhtnZIJi6UQ0oPJCtR-eef_rmZ1UUK9VJypzrSaqE6i6oSqzrT6NK0WvvVw_UablZj_NK7VeuBoDYDTYE0NlS7cLy6VaciE505X3EthcfnvBdTZzUOXhR9wXJ5r</recordid><startdate>200508</startdate><enddate>200508</enddate><creator>Kehinde, Elijah O.</creator><creator>Mojiminiyi, Olusegun A.</creator><creator>Sheikh, Mehraj</creator><creator>Al‐Awadi, Kaleel A.</creator><creator>Daar, Abdallah S.</creator><creator>Al‐Hunayan, Adel</creator><creator>Anim, Jehoram T.</creator><creator>Al‐Sumait, Aisha A.</creator><general>Blackwell Science Ltd</general><general>Blackwell</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200508</creationdate><title>Age‐specific reference levels of serum prostate‐specific antigen and prostate volume in healthy Arab men</title><author>Kehinde, Elijah O. ; Mojiminiyi, Olusegun A. ; Sheikh, Mehraj ; Al‐Awadi, Kaleel A. ; Daar, Abdallah S. ; Al‐Hunayan, Adel ; Anim, Jehoram T. ; Al‐Sumait, Aisha A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3970-cf4c0dbb5c1efbf857eae5be811e7d9bf711f8ae8e18a66fa2615aa8a5f6d4313</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Age Factors</topic><topic>Aged</topic><topic>Arab</topic><topic>Arabs</topic><topic>Asian</topic><topic>Biological and medical sciences</topic><topic>Caucasian</topic><topic>Genital system. Mammary gland</topic><topic>Humans</topic><topic>Investigative techniques, diagnostic techniques (general aspects)</topic><topic>Kuwait - ethnology</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Nephrology. Urinary tract diseases</topic><topic>Oman - ethnology</topic><topic>Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques</topic><topic>Prostate - anatomy & histology</topic><topic>prostate volume</topic><topic>Prostate-Specific Antigen - blood</topic><topic>prostate‐specific antigen</topic><topic>Prostatic Neoplasms - blood</topic><topic>Prostatic Neoplasms - ethnology</topic><topic>Prostatic Neoplasms - pathology</topic><topic>Reference Values</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kehinde, Elijah O.</creatorcontrib><creatorcontrib>Mojiminiyi, Olusegun A.</creatorcontrib><creatorcontrib>Sheikh, Mehraj</creatorcontrib><creatorcontrib>Al‐Awadi, Kaleel A.</creatorcontrib><creatorcontrib>Daar, Abdallah S.</creatorcontrib><creatorcontrib>Al‐Hunayan, Adel</creatorcontrib><creatorcontrib>Anim, Jehoram T.</creatorcontrib><creatorcontrib>Al‐Sumait, Aisha A.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>BJU international</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kehinde, Elijah O.</au><au>Mojiminiyi, Olusegun A.</au><au>Sheikh, Mehraj</au><au>Al‐Awadi, Kaleel A.</au><au>Daar, Abdallah S.</au><au>Al‐Hunayan, Adel</au><au>Anim, Jehoram T.</au><au>Al‐Sumait, Aisha A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Age‐specific reference levels of serum prostate‐specific antigen and prostate volume in healthy Arab men</atitle><jtitle>BJU international</jtitle><addtitle>BJU Int</addtitle><date>2005-08</date><risdate>2005</risdate><volume>96</volume><issue>3</issue><spage>308</spage><epage>312</epage><pages>308-312</pages><issn>1464-4096</issn><eissn>1464-410X</eissn><abstract>OBJECTIVE
To determine age‐specific reference ranges for serum prostate‐specific antigen (PSA) concentration and prostate volumes in a population of healthy Arab men.
SUBJECTS AND METHODS
Blood samples were taken from 396 healthy Arab men (from Kuwait and Oman) aged 15–79 years and from across the social spectrum. Men aged >40 years had a digital rectal examination and transrectal ultrasonography of the prostate to determine prostate volume. The serum PSA level was measured using commercial kits, and age‐specific ranges for PSA levels and prostate volume determined.
RESULTS
The serum PSA ranges (ng/mL) for each age range in Arab men were: 40–49 years, 0–0.9; 60–69, 0–2.7; 70–79, 0–5.5 ng/mL; the respective prostate volumes were 8–22, 9–30 and 10–33 mL. The serum PSA level and prostate volume correlated with age (P < 0.001). Arab men had lower serum PSA levels and prostate volumes than those reported for Caucasians, but similar to those reported for Asians (Japanese and Chinese).
CONCLUSION
These results indicate that Arab men have lower PSA levels and prostate volumes than Caucasians. The levels are slightly lower than those reported in the Japanese and, as in the Japanese, low PSA levels and small prostate volumes might be related to the low incidence of clinical prostate cancer in Arab men.</abstract><cop>Oxford, UK</cop><pub>Blackwell Science Ltd</pub><pmid>16042719</pmid><doi>10.1111/j.1464-410X.2005.05620.x</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1464-4096 |
| ispartof | BJU international, 2005-08, Vol.96 (3), p.308-312 |
| issn | 1464-4096 1464-410X |
| language | eng |
| recordid | cdi_proquest_miscellaneous_68076556 |
| source | Wiley |
| subjects | Adolescent Adult Age Factors Aged Arab Arabs Asian Biological and medical sciences Caucasian Genital system. Mammary gland Humans Investigative techniques, diagnostic techniques (general aspects) Kuwait - ethnology Male Medical sciences Middle Aged Nephrology. Urinary tract diseases Oman - ethnology Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Prostate - anatomy & histology prostate volume Prostate-Specific Antigen - blood prostate‐specific antigen Prostatic Neoplasms - blood Prostatic Neoplasms - ethnology Prostatic Neoplasms - pathology Reference Values |
| title | Age‐specific reference levels of serum prostate‐specific antigen and prostate volume in healthy Arab men |
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