Langerhans cell histiocytosis of the thyroid

Langerhans cell histiocytosis, also known as histiocytosis X, has a broad clinical spectrum and highly variable prognosis. Its localization in the thyroid gland is relatively rare and presents particular diagnostic and therapeutic difficulties. A 38-year-old man consulted for an anterior cervical ma...

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Bibliographic Details
Published in:La Presse médicale (1983) 2006-06, Vol.35 (6 Pt 1), p.977-979
Main Authors: Oudidi, Abdellatif, Hachimi, Hicham, El Alami, Med Nourredine
Format: Article
Language:fre
Subjects:
Adult
Histiocytosis, Langerhans-Cell - pathology
Histiocytosis, Langerhans-Cell - surgery
Humans
Male
Thyroid Gland - metabolism
Thyroid Gland - pathology
Thyroid Gland - surgery
Thyrotropin - metabolism
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Summary:Langerhans cell histiocytosis, also known as histiocytosis X, has a broad clinical spectrum and highly variable prognosis. Its localization in the thyroid gland is relatively rare and presents particular diagnostic and therapeutic difficulties. A 38-year-old man consulted for an anterior cervical mass that dated back to childhood but which had grown substantially in volume over the past seven months. The workup indicated a left thyroid nodule. We performed a thyroid lobectomy with isthmusectomy. Immunohistochemical and pathology analyses showed Langerhans cell histiocytosis of the thyroid. The immediate postoperative course and subsequent outcome were good (follow-up: 34 months). Diagnosis and treatment of Langerhans cell histiocytosis in the thyroid gland often require multidisciplinary cooperation to analyze clinical, radiological, and pathology findings.
ISSN:0755-4982
DOI:10.1016/S0755-4982(06)74731-5