Spongy gel-like layered double hydroxide-alkaline phosphatase nanohybrid as a biosensing material

Formation of new bio-nanohybrid material was obtained by immobilization of alkaline phosphatase within a Mg(2)Al LDH by "soft chemistry" coprecipitation synthesis, resulting in an original spongy gel-like morphology allowing the preservation of the enzyme structure and activity even at low...

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Bibliographic Details
Published in:Chemical communications (Cambridge, England) England), 2008-01 (13), p.1554-1556
Main Authors: Geraud, Erwan, Prevot, Vanessa, Forano, Claude, Mousty, Christine
Format: Article
Language:English
Subjects:
Alkaline Phosphatase - chemistry
Biosensing Techniques
Enzyme Activation
Gels - chemistry
Hydrogen-Ion Concentration
Hydroxides - chemistry
Metals - chemistry
Nanostructures - chemistry
Particle Size
Powder Diffraction
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Summary:Formation of new bio-nanohybrid material was obtained by immobilization of alkaline phosphatase within a Mg(2)Al LDH by "soft chemistry" coprecipitation synthesis, resulting in an original spongy gel-like morphology allowing the preservation of the enzyme structure and activity even at low pH values thanks to the buffering property of the basic host structure.
ISSN:1359-7345
1364-548X
DOI:10.1039/b715385f