Iron supplementation: oral tablets versus intramuscular injection

Non-anemic, iron depleted women were randomly assigned to an injection group (IG) or oral group (OG) to assess which method is more efficient for increasing iron stores over a short time period. IG received a course of 5 x 2 mL intramuscular injections over 10 d, and OG received one tablet daily for...

Full description

Saved in:
Bibliographic Details
Published in:International journal of sport nutrition and exercise metabolism 2006-04, Vol.16 (2), p.180-186
Main Authors: Dawson, B, Goodman, C, Blee, T, Claydon, G, Peeling, P, Beilby, J, Prins, A
Format: Article
Language:English
Subjects:
Administration, Oral
Adult
dietary mineral supplements
Dietary Supplements
Female
ferritin
Ferritins - analysis
hemoglobin
Hemoglobins - analysis
human nutrition
Humans
Injections, Intramuscular - methods
intramuscular injection
iron
Iron - blood
Iron - deficiency
Iron, Dietary - administration & dosage
Iron, Dietary - pharmacokinetics
Iron, Dietary - therapeutic use
nutrient deficiencies
nutritional status
oral administration
Treatment Outcome
women
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Non-anemic, iron depleted women were randomly assigned to an injection group (IG) or oral group (OG) to assess which method is more efficient for increasing iron stores over a short time period. IG received a course of 5 x 2 mL intramuscular injections over 10 d, and OG received one tablet daily for 30 d. Fourteen, 21 and 28 d after commencing supplementation, ferritin concentration in OG significantly increased from baseline (means +/- standard error: 27 +/- 3 to 40 +/- 5 to 41 +/- 5 to 41 +/- 5 microgram/L; P < 0.01). Similarly, on days 15, 20, and 28 post the first injection, ferritin concentration in IG significantly increased from baseline (means +/- standard error: 20 +/- 2 to 71 +/- 17 to 63 +/- 11 to 63 +/- 7 microgram/L; P < 0.01), and was also significantly greater than OG at day 15 and 28 (P < 0.05). Iron injections are significantly more effective (both in time and degree of increase) in improving ferritin levels over 30 d than oral tablets.
ISSN:1526-484X
1543-2742
DOI:10.1123/ijsnem.16.2.180