Cogitation about free radicals and oxidative stress--an old concept with many new limitations

Since its creation, the concept of OS became very popular. Manifestations of the OS were investigated, verified, proved and disproved in thousands of studies. However, the enormous amount of knowledge about OS that accumulated in the last decades had dual influence: it extended the original concept...

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Bibliographic Details
Published in:General physiology and biophysics 2007-06, Vol.26 (2), p.71-74
Main Author: Ziegelhöffer, A
Format: Article
Language:English
Subjects:
Animals
Antioxidants - metabolism
Cell Compartmentation - physiology
Cellular Senescence - physiology
Free Radicals - analysis
Free Radicals - metabolism
Humans
Oxidative Stress - physiology
Reactive Oxygen Species - analysis
Reactive Oxygen Species - metabolism
Terminology as Topic
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Summary:Since its creation, the concept of OS became very popular. Manifestations of the OS were investigated, verified, proved and disproved in thousands of studies. However, the enormous amount of knowledge about OS that accumulated in the last decades had dual influence: it extended the original concept of OS considerably, often even in an undesirable way, but it also pointed to its vulnerability. The present treatise is a cogitation about some main limitations that can make the original concept of OS outdated. No matter whether outdated or only less exact, it would be better to think it over three times prior using the term OS.
ISSN:0231-5882