Trace element status in Saudi patients with established atherosclerosis

Traditional coronary risk factors do not fully explain variations in the incidence of cardiovascular disease (CVD). Epidemiological studies have implicated perturbations in selenium, copper, and zinc metabolism in the aetiology of CVD. However, these studies have been principally undertaken in Cauca...

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Bibliographic Details
Published in:Journal of trace elements in medicine and biology 2006-01, Vol.20 (2), p.105-114
Main Authors: Alissa, Eman M., Bahjri, Suhad M., Ahmed, Waqar H., Al-ama, Nabeel, Ferns, Gordon A.A.
Format: Article
Language:English
Subjects:
Adult
Age Factors
Aged
Atherosclerosis
Atherosclerosis - blood
Atherosclerosis - urine
Copper
Copper - blood
Copper - urine
Demography
Diet
Glutathione Peroxidase - blood
Glutathione Peroxidase - urine
Humans
Lipid Peroxides - blood
Lipid Peroxides - urine
Male
Middle Aged
Multivariate Analysis
Risk Factors
Saudi Arabia
Selenium
Selenium - blood
Selenium - urine
Superoxide Dismutase - blood
Superoxide Dismutase - urine
Trace Elements - blood
Trace Elements - urine
Zinc
Zinc - blood
Zinc - urine
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Summary:Traditional coronary risk factors do not fully explain variations in the incidence of cardiovascular disease (CVD). Epidemiological studies have implicated perturbations in selenium, copper, and zinc metabolism in the aetiology of CVD. However, these studies have been principally undertaken in Caucasian populations, in whom trace element intake is generally sufficient. We have measured serum and urine selenium, copper, and zinc; and superoxide dismutase, glutathione peroxidase, and lipid peroxide concentrations in 130 Saudi male subjects with established CVD, and 130 age-matched controls. Diabetes mellitus, positive smoking habit ( p
ISSN:0946-672X
1878-3252
DOI:10.1016/j.jtemb.2005.10.004