Advanced oxidation protein products (AOPP) and high-sensitive C-reactive protein (hs-CRP) in an “atheroma-free model”: Down's syndrome

Murdoch et al. in 1977 called Down syndrome an “atheroma-free model.” In this preliminary study, we investigated advanced oxidation protein products (AOPP) and high-sensitive C-reactive protein (hs-CRP) in 47 age-matched Down syndrome patients and 20 age-matched healthy controls. In these healthy pa...

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Bibliographic Details
Published in:International journal of cardiology 2006-11, Vol.113 (3), p.427-429
Main Authors: Goi, G., Baquero-Herrera, C., Licastro, F., Dogliotti, G., Corsi, M.M.
Format: Article
Language:English
Subjects:
Adolescent
Adult
AOPP-CRP
Atherosclerosis
Atherosclerosis (general aspects, experimental research)
Atherosclerosis - blood
Biological and medical sciences
Blood and lymphatic vessels
C-Reactive Protein - analysis
Cardiology. Vascular system
Child
Child, Preschool
Chromosome aberrations
Down syndrome
Down Syndrome - blood
Down Syndrome - metabolism
Humans
Medical genetics
Medical sciences
Middle Aged
Oxidation-Reduction
Proteins - metabolism
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Summary:Murdoch et al. in 1977 called Down syndrome an “atheroma-free model.” In this preliminary study, we investigated advanced oxidation protein products (AOPP) and high-sensitive C-reactive protein (hs-CRP) in 47 age-matched Down syndrome patients and 20 age-matched healthy controls. In these healthy patients, we detected no new biochemical risk factors for atherosclerosis, such as AOPP and hs-CRP, so risks are probably considerably lower.
ISSN:0167-5273
1874-1754
DOI:10.1016/j.ijcard.2005.10.019