Relevance of Chronic Kidney Disease Classification (K/DOQI) in Renal Transplant Patients

The National Kidney Foundation has developed guidelines for diagnosis and classification of chronic kidney disease (CKD) but it is not known whether they are applicable to renal transplant patients. This study analyzed the prevalence, the complications, and the influence of the CKD stage on the pres...

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Bibliographic Details
Published in:Transplantation proceedings 2006-10, Vol.38 (8), p.2402-2403
Main Authors: Fernandez-Fresnedo, G., de Francisco, A., Ruiz, J.C., Cotorruelo, J.G., Alamillo, C.G., Valero, R., Castañeda, O., Zalduendo, B., Izquierdo, M.J., Arias, M.
Format: Article
Language:English
Subjects:
Adult
Aged
Biological and medical sciences
Creatinine - blood
Cross-Sectional Studies
Follow-Up Studies
Fundamental and applied biological sciences. Psychology
Fundamental immunology
Glomerular Filtration Rate
Humans
Kidney Failure, Chronic - blood
Kidney Failure, Chronic - classification
Kidney Failure, Chronic - surgery
Kidney Transplantation
Kidneys
Lipoproteins - blood
Medical sciences
Middle Aged
Nephrology. Urinary tract diseases
Parathyroid Hormone - blood
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Tissue, organ and graft immunology
Treatment Outcome
Urinary system involvement in other diseases. Miscellaneous
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Summary:The National Kidney Foundation has developed guidelines for diagnosis and classification of chronic kidney disease (CKD) but it is not known whether they are applicable to renal transplant patients. This study analyzed the prevalence, the complications, and the influence of the CKD stage on the presence of complications in 506 stable transplant recipients. The mean age of the patients was 52.9 ± 12 years, 34% were men, and the mean time after transplantation was 9.56 ± 6.18 years. CKD was present in 90.3% with 9.9% were in CKD stages 4 or 5 with glomerular filtration rates lower than 30 mL/min per 1.73 m 2. The prevalence of anemia, phospho-calcium metabolism disorders, hypertriglyceridemia, and hypertension increased with the stage of CKD. We concluded that CKD and the complications of CKD were highly prevalent in renal transplant recipients. The classification of renal transplant patients by CKD stage may help clinicians to identify patients at increased risk and to target appropriate therapy to improve outcomes.
ISSN:0041-1345
1873-2623
DOI:10.1016/j.transproceed.2006.08.051