Measurements of gastric emptying of low‐ and high‐nutrient liquids using 3D ultrasonography and scintigraphy in healthy subjects

Scintigraphy represents the ‘gold standard’ for the measurement of gastric emptying. Recent studies suggest that three‐dimensional (3D) ultrasonography may allow a precise measure of gastric emptying, given the capacity for accurate volume calculations of the stomach. The aim of this study was to co...

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Bibliographic Details
Published in:Neurogastroenterology and motility 2006-12, Vol.18 (12), p.1062-1068
Main Authors: Gentilcore, D., Hausken, T., Horowitz, M., Jones, K. L.
Format: Article
Language:English
Subjects:
Adult
Eating
Female
gastric emptying
Gastric Emptying - physiology
Humans
imaging
Imaging, Three-Dimensional
Male
Radionuclide Imaging - methods
Radiopharmaceuticals
scintigraphy
Stomach - diagnostic imaging
Technetium Tc 99m Sulfur Colloid
three‐dimensional
two‐dimensional
Ultrasonography - methods
ultrasound
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Summary:Scintigraphy represents the ‘gold standard’ for the measurement of gastric emptying. Recent studies suggest that three‐dimensional (3D) ultrasonography may allow a precise measure of gastric emptying, given the capacity for accurate volume calculations of the stomach. The aim of this study was to compare measurements of gastric emptying of both low‐ and high‐nutrient drinks by 3D ultrasonography with scintigraphy. Ten healthy young subjects (6M, 4F, age 23.5 ± 1.5 years) were studied on 2 days. Concurrent measurements of gastric emptying by scintigraphy and 3D ultrasonography were performed after ingestion of 500 mL beef soup (12 kcal) or 300 ml dextrose (25% w/v) (314 kcal) labelled with 20 MBq 99mTc‐sulphur colloid. There was no significant difference between scintigraphic and ultrasonographic 50% emptying times (T50s) (soup: 27.7 ± 4.8 min vs 23.8. ± 4.8 min; dextrose: 122.2 ± 13.3 min vs 131.9 ± 10.2 min). There was a close correlation between scintigraphic and ultrasonographic T50s for both soup (r = 0.92, P = 0.0005) and dextrose (r = 0.88, P = 0.0007). For the T50s, the limits of agreement were −15.2 min and +8.1 min for the soup (mean difference −3.6 min) and −35.3 min and +47.6 min for dextrose (mean difference +6.2 min). 3D ultrasonography provides a valid measure of gastric emptying of liquid meals in healthy subjects.
ISSN:1350-1925
1365-2982
DOI:10.1111/j.1365-2982.2006.00830.x