Mitogenic effect of Carthamus lanatus extracts, fractions and constituents

Extracts, fractions and constituents of Carthamus lanatus were tested for their mitogenic effect on bone marrow cells in mice. Most of the studied samples inhibited cell proliferation and only the flavonoid glycoside rutin caused increasing of mitotic activity.

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Bibliographic Details
Published in:Fitoterapia 2006-12, Vol.77 (7), p.608-610
Main Authors: Topashka-Ancheva, Margarita N., Taskova, Rilka M., Handjieva, Nedjalka V.
Format: Article
Language:English
Subjects:
Animals
Biological and medical sciences
Bone Marrow Cells - drug effects
Carthamus
Carthamus lanatus
Cell Cycle - drug effects
Female
General pharmacology
Male
Medical sciences
Mice
Mice, Inbred ICR
Mitogens - administration & dosage
Mitogens - pharmacology
Mitogens - therapeutic use
Mitotic activity
Pharmacognosy. Homeopathy. Health food
Pharmacology. Drug treatments
Phytotherapy
Plant Extracts - administration & dosage
Plant Extracts - pharmacology
Plant Extracts - therapeutic use
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Description
Summary:Extracts, fractions and constituents of Carthamus lanatus were tested for their mitogenic effect on bone marrow cells in mice. Most of the studied samples inhibited cell proliferation and only the flavonoid glycoside rutin caused increasing of mitotic activity.
ISSN:0367-326X
DOI:10.1016/j.fitote.2006.06.014