Schizo-obsessive and obsessive-compulsive disorder: Comparison of clinical characteristics and neurological soft signs

The purpose of the study was to examine whether schizophrenia with obsessive-compulsive disorder (OCD) represents a severe form of OCD-spectrum disorders on the basis of neurological soft signs (NSS) and obsessive-compulsive (OC) symptoms. Sixteen patients with OCD-schizophrenia, 25 OCD patients and...

Full description

Saved in:
Bibliographic Details
Published in:Psychiatry research 2006-12, Vol.145 (2), p.241-248
Main Authors: Sevincok, Levent, Akoglu, Aybars, Arslantas, Hülya
Format: Article
Language:English
Subjects:
Adult
Adult and adolescent clinical studies
Affect
Anxiety disorders. Neuroses
Biological and medical sciences
Brain - physiopathology
Demography
Female
Humans
Male
Medical sciences
Neurological soft signs
Obsessive-compulsive disorder
Obsessive-Compulsive Disorder - diagnosis
Obsessive-Compulsive Disorder - physiopathology
Obsessive-compulsive disorders
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
Psychoses
Psychotic Disorders - diagnosis
Psychotic Disorders - physiopathology
Schizo-obsessive disorder
Schizophrenia
Severity of Illness Index
Surveys and Questionnaires
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The purpose of the study was to examine whether schizophrenia with obsessive-compulsive disorder (OCD) represents a severe form of OCD-spectrum disorders on the basis of neurological soft signs (NSS) and obsessive-compulsive (OC) symptoms. Sixteen patients with OCD-schizophrenia, 25 OCD patients and 23 healthy controls (HC) were studied. Scales for the Assessment of Positive (SAPS) and Negative Symptoms (SANS), Clinical Global Impressions Scale and Yale-Brown Obsessive-Compulsive Scale (Y-BOCS) were used to assess the schizophrenic and OC symptomatology. NSS were evaluated with the Neurological Evaluation Scale (NES). OCD-schizophrenics had significantly higher scores on total NES than HC. The patients with OCD were more likely to have total Y-BOCS and subscale scores of compulsions than patients with OCD-schizophrenia. The rate of symmetry obsessions and cleaning/washing compulsions were significantly higher in patients with OCD compared to OCD-schizophrenics. We have found no correlation of OC symptoms with schizophrenic symptomatology. Our findings may suggest that OCD-schizophrenia is a distinct subtype of schizophrenia, not a more severe form of OCD-spectrum disorder.
ISSN:0165-1781
1872-7123
DOI:10.1016/j.psychres.2005.11.010