Gonadotrophin releasing hormone analogues for the management of placenta accreta: A novel concept

Appiah-Sakyi et al present a case of a 31-year-old primiparous who had a retained placenta, after a forceps delivery. At manual removal of placenta, the patient was found to have a morbidly adherent placenta, which could not be completely separated, therefore a large portion was retained in the fund...

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Bibliographic Details
Published in:Journal of obstetrics and gynaecology 2007-07, Vol.27 (5), p.527-528
Main Authors: Appiah-Sakyi, K., Fatima, Z., Anjum, Z. K.
Format: Article
Language:English
Subjects:
Adult
Childbirth & labor
Female
Gonadotropin-Releasing Hormone - analogs & derivatives
Goserelin - therapeutic use
Hormones
Humans
Magnetic Resonance Imaging
Obstetrics
Placenta Accreta - diagnosis
Placenta Accreta - drug therapy
Pregnancy
Reproductive system
Treatment Outcome
Ultrasonography
Womens health
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Summary:Appiah-Sakyi et al present a case of a 31-year-old primiparous who had a retained placenta, after a forceps delivery. At manual removal of placenta, the patient was found to have a morbidly adherent placenta, which could not be completely separated, therefore a large portion was retained in the fundus. Placenta accreta is an abnormally firm attachment of the placenta to the uterine muscle, where the anchoring placental villus is in direct contact with the myometrium. Traditionally, gonadotrophin releasing hormone (GnRH) analogues are used for the management of several common gynaecological conditions such as endometriosis, fibroid, menorrhagia and infertility. The decision to use GnRH analogues in this case was based primarily on patient reluctance to continue the methotrexate injections.
ISSN:0144-3615
1364-6893
DOI:10.1080/01443610701467309